Results 71 to 80 of about 660,066 (290)
Regulation of mitochondrial permeability transition pore by PINK1 [PDF]
, 2012 Background: Loss-of-function mutations in PTEN-induced kinase 1 (PINK1) have been linked to familial Parkinson’s disease, but the underlying pathogenic mechanism remains unclear.
Caballero, Erica +7 more
core +3 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Emerging role of the pentose phosphate pathway in hepatocellular carcinoma [PDF]
, 2017 In recent years, there has been a revival of interest in metabolic changes of cancer cells as it has been noticed that malignant transformation and metabolic reprogramming are closely intertwined.
Columbano, Amedeo +2 more
core +2 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Can systemic resistances contribute to ecologically based IPM control of nematodes in pineapple? [PDF]
, 2011 Pineapple monoculture and the use of pesticides reduced the biodiversity in the agrosystems and increased the imbalance between pathogenic and beneficial organisms.
Marie-Alphonsine, Paul-Alex +1 more
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
CropsAmong heavy metals, cadmium (Cd) is shown to have adverse consequences for plants. Due to its harmful nature and ability to move through the soil–plant system, it is a very worrying element for soil experts and plant physiologists.
Said Bouhraoua +9 more
doaj +1 more source
The influence of tillage on selected biological parameters
Plant, Soil and Environment, 2006 The influence of tillage (conventional and non-tillage) on selected soil microbial properties was studied. The experiment focused on tillage that was launched in Prague-Ruzyne in 1997. The experiment included the following variants: conventional tillage,
O. Mikanová +3 more
doaj +1 more source
Comparison between conventional and alternative peeling methods on peeling efficiencies of Malaysian 'Chok Anan' mango (Mangifera indica L.) fruit [PDF]
, 2017 Fruit industries require convenient peeling method, especially during puree processing to prevent deterioration of fruit quality and product loss. Therefore, manual, chemical (sodium hydroxide/NaOH) and enzymatic (Pectinex Ultra SP-L) peeling methods ...
Hussain, Norhayati +3 more
core +1 more source
The Urea Carboxylase and Allophanate Hydrolase Activities of Urea Amidolyase Are Functionally Independent [PDF]
, 2016 Urea amidolyase (UAL) is a multifunctional biotin-dependent enzyme that contributes to both bacterial and fungal pathogenicity by catalyzing the ATP-dependent cleavage of urea into ammonia and CO2.
Bahler +48 more
core +2 more sources