Results 121 to 130 of about 1,215,941 (358)
Ovine 6-phosphogluconate dehydrogenase (6PGD) is an enzyme of the pentose phosphate pathway, providing the necessary compounds of NADPH for the synthesis of fatty acids.
Stamatina Trivizaki +4 more
doaj +1 more source
Allosteric regulation of deubiquitylase activity through ubiquitination
Ataxin-3, the protein responsible for spinocerebellar ataxia type-3, is a cysteine protease that specifically cleaves poly-ubiquitin chains and participates in the ubiquitin proteasome pathway.
Serena eFaggiano +9 more
doaj +1 more source
Printed, Flexible Lactate Sensors: Design Considerations Before Performing On-Body Measurements. [PDF]
This work reports the process of sensor development, optimization, and characterization before the transition to on-body measurements can be made. Sensors using lactate oxidase as a sensing mechanism and tetrathiafulvalene as a mediator were optimized ...
Arias, Ana Claudia +4 more
core +1 more source
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Production of deoxy-thymidine-diphosphate (TDP)-sugars as substrates of glycosyltransferases, has been one of main hurdles for combinatorial antibiotic biosynthesis, which combines sugar moiety with aglycon of various antibiotics. Here, we report the one-
Kang, Young Bok (Abraham) +10 more
core
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
One of the kratom (Mitragyna speciosa Korth.) products in Kapuas Hulu is fermented kratom tea powder, produced by the enzymatic oxidation process, which is very different from the processing of black tea.
Brigita Ratna Harsanti +2 more
doaj +1 more source
The stains of Candida albicans and Trichosporon beigelii isolated from astatic reservoir show a higher enzymatic activity than the strains isolated from lake. The results obtained confirm earlier suspicions that the morphological differentiation of micro-
Maria Dynowska, Anna Biedunkiewicz
doaj +1 more source
Can bio-inspired information processing steps be realized as synthetic biochemical processes?
We consider possible designs and experimental realiza-tions in synthesized rather than naturally occurring bio-chemical systems of a selection of basic bio-inspired information processing steps.
Katz, Evgeny, Privman, Vladimir
core +1 more source

