Results 111 to 120 of about 395,671 (307)

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

Automation of enzyme-linked immunosorbent assay (ELISA). [PDF]

, 1979
A prototype of automatized enzyme-linked immunosorbent assay (ELISA) in tubes is described, using a commercially available basic material, easily modified. Nine hundred samples could be completely studied in a day by only one person.
Carlier, Yves, Capron, André, Bout, D
core  

Monitoring of Salivary Secretory Immunoglobulin A Quantified Two Methods During High-Altitude Volleyball Training Camp

Physiologia
Background/Objectives: Volleyball training camps are known to reduce salivary secretory immunoglobulin A (s-SIgA); however, when it begins to decrease is unclear.
Ryota Sone, Kenji Yamamoto, Shinsuke Tamai, Honoka Goji, Kenji Ohishi   +4 more
doaj   +1 more source

Targeting UXS1‐Dependent Glucuronate Detoxification Potentiates Metformin's Anti‐Tumor Efficacy in Lung Adenocarcinoma

Advanced Science, EarlyView.
This study reveals that metformin promotes glucuronic acid metabolism in lung adenocarcinoma by activating UGDH S476 phosphorylation and enhancing the conversion of UDPG to UDPGA based on metabolomics analysis. Through compound virtual screening, it is found that plantainoside targeting UGDH downstream UXS1 leads to UDPGA toxicity accumulation ...
Qihai Sui, Zhencong Chen, Guangyao Shan, Zhengyang Hu, Xing Jin, Jiaqi Liang, Yanjun Yi, Jiacheng Yin, Haochun Shi, Xifei Jiang, Junjie Xi, Zongwu Lin, Cheng Zhan, Fenghao Sun, Wei Jiang   +14 more
wiley   +1 more source

Gut Microbiota Regulates Systemic Inflammatory Response and Compensatory Anti‐Inflammatory Response Syndromes by Targeting PF4+ Macrophages in Acute Pancreatitis

Advanced Science, EarlyView.
ABSTRACT Acute pancreatitis (AP) begins with pancreatic local inflammation, leading to the onset of systemic inflammatory response syndrome (SIRS), followed by compensatory anti‐inflammatory response syndrome (CARS), which causes immune paralysis and higher mortality rate.
Liwei Liu, Guanqun Li, Dongxu Lu, Haoran Ding, Tianqi Lu, Yuhang Sui, Can Zhang, Yu Xie, Rui Kong, Hua Chen, Xuewei Bai, Hongtao Tan, Dongbo Xue, Xianzhi Meng, Le Li, Bei Sun   +15 more
wiley   +1 more source

Prevalence (percentage) of cross-reactions observed in immunodiffusion and enzyme-linked immunosorbent assay tests. [PDF]

, 2015
DID: double agar gel immunodiffusion test; ELISA: enzyme-linked immunosorbent assay; 1: antigen of Aspergillus fumigatus; 2: pool of antigens: A. fumigatus, A. flavus e A.
Lídia Raquel de Carvalho (557816), Rinaldo Poncio Mendes (365963), Tatiane Fernanda Sylvestre (553786), Daniela Vanessa Moris (557813), Priscila Zacarias de Azevedo (783296), Ricardo de Souza Cavalcante (553785), Maria Luiza Cotrim Sartor de Oliveira (513131)   +6 more
core   +1 more source

Standardisation of an indirect enzyme-linked immunosorbent assay for the detection [PDF]

Veterinaria Italiana, 2011
An indirect enzyme-linked immunosorbent assay (ELISA) was evaluated for the detection of Brucella antibodies in milk from water buffalo (Bubalus bubalis Linnaeus, 1758). The test accuracy was evaluated on milk samples from the Campania Region in Italy. A
Manuela Tittarelli, Barbara Bonfini, Fabrizio De Massis, Armando Giovannini, Massimo Scacchia   +4 more
doaj  

Frequency of human toxocariasis in Jos, Plateau State, Nigeria

Memorias do Instituto Oswaldo Cruz, 2000
The enzyme-linked immunosorbent assay (Elisa) was used to examine sera of 104 children and adults in Jos, Plateau State, Nigeria for anti-toxocaral antibodies, out of which 31 (29.8%) were reactive. The seropositive rates were 30.4% for adults, 29.6% for
OO Ajayi, DD Duhlinska, SM Agwale, M Njoku   +3 more
doaj   +1 more source

LC3B Mediated SETDB1‐Accounted Alcoholic Steatohepatitis via Lipidation‐Dependent LAP and Lipidation‐Independent Nuclear Stabilization

Advanced Science, EarlyView.
SETDB1 is progressively downregulated in ALD, correlating with disease severity. SETDB1 deficiency impairs LAP by disrupting Rubicon membrane localization, leading to defective lipid droplet clearance. Concurrently, loss of SETDB1 reduces nuclear LC3B, causing R‐loop accumulation and cGAS‐STING‐driven inflammation. Lipidated LC3B mediates LAP‐dependent
Yi Zhang, Tan Wei, Jiahang Wu, Chuixu Lin, Dongbo Zhu, Yanhui Li, Shuting Shi, Shishun Huang, Leiming Jiang, Hongzhi Wang, Meiqi Song, Pengfei Gao, Xu Wu, Mingjian Fan, Chaofeng Wei, Qian Wang, Lihui Qu, Zhigang Wang   +17 more
wiley   +1 more source

CARBENDAZIM RESIDUES QUANTIFICATION IN GREEN LETTUCE BY ENZYME-LINKED IMMUNOSORBENT ASSAY

Food and Environment Safety, 2022
Carbendazim is a fungicide that is not approved for use in the European Union, but is used in some other countries to preserve agricultural crops. Enzyme-linked immunosorbent assay (ELISA) become a viable alternative to traditional instrumental methods ...
Veronica TANASA, Madalina DOLTU, Dorin SORA, Radu I. TANASA, Narcisa BABEANU   +4 more
doaj