Results 121 to 130 of about 3,900,452 (305)

Zika IgM antibody-capture enzyme-linked immunosorbent assay

This document describes the use of an IgM antibody capture enzyme-linked immunosorbent assay (MAC-ELISA) for the presumptive detection of antibodies to Zika virus in persons meeting Centers for Disease Control and Prevention (CDC) clinical and/or ...

core  

Development of an indirect competitive enzyme-linked immunosorbent assay for screening ethopabate residue in chicken muscle and liver

, 2017
Development of an indirect competitive enzyme-linked immunosorbent assay for screening ethopabate residue in chicken muscle and liver.
Daomin Li, Zhaozhou Li, Xiujin Chen, Zhili Li, Yao Wang, Li Cao, Yuze Hou, Hongli Gao, Songbiao Li   +8 more
core   +1 more source

Somatic Evolution of a Germline Antibody Expands its Breadth to Neutralize Early SARS‐CoV‐2 Omicron Variants

Advanced Science, EarlyView.
Engineering of the 148‐germline (148‐GL) antibody reveals a roadmap for overcoming SARS‐CoV‐2 viral escape. By introducing four specific somatic hypermutations, the resulting 148‐M4 variant restores potent neutralization against Omicron BA.1 and BA.4/5.
Huibin Lv, Ziqi Feng, Qi Wen Teo, Chunke Chen, Akshita B. Gopal, Danbi Choi, Timothy J. C. Tan, Yun Sang Tang, Lewis Siu, Armita Nourmohammad, Roberto Bruzzone, Ian A. Wilson, Meng Yuan, Nicholas C. Wu, Chris K. P. Mok   +14 more
wiley   +1 more source

Evaluation of Salivary Leptin Levels in Healthy Subjects and Patients with Advanced Periodontitis

Frontiers in Dentistry, 2016
Objectives: Leptin is a hormone-like protein produced by the adipose tissue. It plays an important role in protection of host against inflammation and infection.
Afshin Khorsand, Mojtaba Bayani, Siamak Yaghobee, Sepehr Torabi, Mohammad Javad Kharrazifard, Fatemeh Mohammadnejhad   +5 more
doaj  

Single‐Step Electrochemical Aptasensor for Melatonin Detection in Unprocessed Plasma

Advanced Science, EarlyView.
Melatonin is a well‐known biomarker with significant potential for clinical use in diagnosing circadian rhythm sleep disorders (CRSDs) and monitoring patients with documented circadian clock disruption. An electrochemical aptamer‐based biosensor (E‐aptasensor), employing an optimized population of melatonin aptamers, has been proposed as a solution for
Hamed Shieh, Arash Khorrami Jahromi, Fernando Gonzales‐Aste, Sajad Shiekh, Roozbeh Siavash Moakhar, Sahar Sadat Mahshid, Sara Mahshid   +6 more
wiley   +1 more source

Investigation of cryptosporidiosis by enzyme-linked immunosorbent assay and microscopy in children with diarrhea

, 2008
Objective: To investigate the frequency of cryptosporidiosis by enzyme-linked immunosorbent assay (ELISA) and microscopy and its relationship with ...
Yılmaz, Hasan, Cicek, Mutalip, Tas-Cengiz, Zeynep   +2 more
core  

A Rare De Novo Missense Mutation in IFT122 Confers a Genetic Susceptibility Factor of Idiopathic Pediatric Uveitis Via Trio‐based Whole‐Exome Sequencing

Advanced Science, EarlyView.
A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...
Qian Zhou, Jiaxing Huang, Yilin Wang, Xingran Li, Xianyang Liu, Lingyu Dai, Hongshun Li, Qingfeng Wang, Jiangyi Liu, Guannan Su, Wanyun Zhang, Yang Deng, Qingfeng Cao, Yujie Lai, Xiang Luo, Changwei Huang, Ling Chen, Shengping Hou, Peizeng Yang   +18 more
wiley   +1 more source

Automation of enzyme-linked immunosorbent assay (ELISA).

, 1979
A prototype of automatized enzyme-linked immunosorbent assay (ELISA) in tubes is described, using a commercially available basic material, easily modified. Nine hundred samples could be completely studied in a day by only one person.
Carlier, Yves, Capron, André, Bout, D
core  

The CXCL5/CXCR2 Axis Attenuates Ferroptosis in Intrahepatic Cholangiocarcinoma Through the Positive Feedback Loop Between PTGS2 Transcriptional Activation and Neutrophil Recruitment

Advanced Science, EarlyView.
The CXCL5/CXCR2 axis directly inhibits ferroptosis in ICC cells by activating the NF‐κB/PTGS2 pathway. Meanwhile, the CXCL5/CXCR2 axis recruits N2 TANs, and the activated PTGS2 promotes the secretion of TNF‐α from the recruited N2 TANs via the CCL2/CCL7/CCR2 pathway, thereby activating the NF‐κB/PTGS2 axis and forming a positive feedback loop, which ...
Chanqi Ye, Kefeng Lin, Shuyao Yang, Yan Zhang, Wenli Gao, Jiaqi Chen, Ying Dong, Rui Bai, Yang Tian, Minghao Wang, Zhijun Yuan, Yuxiao Ma, Yuqin He, Ruyin Chen, Wenguang Fu, Qi Jiang, Qiong Li, Jian Ruan   +17 more
wiley   +1 more source

SPARC Drives Podocyte Mitochondrial Damage and Ferroptosis in Diabetic Kidney Disease Following Klotho Deficiency

Advanced Science, EarlyView.
Klotho deficiency promotes podocyte mitochondrial dysfunction and ferroptosis through activation of the PKCα/CUX1/SPARC/TGFβ‐RII axis. SPARC emerges as a key mediator linking Klotho loss to podocyte injury in DKD and other kidney injury models, suggesting broader implications for CKD progression.
Qing Yang, Huimin Jiang, Chenyang Xiong, Xindi Zhou, Qinqin Tan, Han Xiao, Lan Qiu, Chun Gan, Yaxi Chen, Haiping Yang, Wei Jiang, Qiu Li   +11 more
wiley   +1 more source