Results 121 to 130 of about 395,671 (307)

Anti-Toxoplasma gondii antibody detection in serum and urine samples by enzyme-linked immunosorbent assay in HIV-infected patients

Indian Journal of Pathology and Microbiology, 2013
Background: Toxoplasmosis is a common parasitic infection of man, and reactivation of latent disease in HIV-infected patients can cause fatal encephalitis. Diagnosis depends on demonstration of parasite-specific antibodies in serum.
Sayan Bhattacharyya, Sumeeta Khurana, Mohan Lal Dubey   +2 more
doaj   +1 more source

Quantification of Cibenzoline by Enzyme-Linked Immunosorbent Assay

YAKUGAKU ZASSHI, 2007
We have developed an enzyme-linked immunosorbent assay (ELISA) suitable for routine monitoring of serum levels of cibenzoline. Anti-cibenzoline antibody was obtained by immunizing rabbits with cibenzoline conjugated with bovine serum albumin using N-(4-maleimidobutyryloxy)succinimide as a heterobifunctional coupling agent. An enzyme marker was prepared
SAITA, Tetsuya, TOKUNAGA, Akira, EGOSHI, Masayoshi, TOKUSHIMA, Hideaki, FUJITO, Hiroshi   +4 more
openaire   +3 more sources

Electroacupuncture Improves the Learning and Memory by Modulating Hippocampal Glucose Metabolism through IGF1/IGF1R Signaling in Alzheimer's Disease

Advanced Science, EarlyView.
Electroacupuncture (EA) ameliorates learning and memory function in 5×FAD mice by regulating the brain glucose metabolic network. This neuroprotective effect is closely related to enhancing neuronal energy utilization via the IGF1/IGF1R signaling pathway.
Shengxiang Liang, Qingqing Zhang, Xiuxiu Wang, Lixin Peng, Xinru Ji, Jiawei Wang, Yusi Zhang, Jiayang Huang, Junchao Yang, Shiqi Zhan, Yiping Xiao, Weilin Liu, Lidian Chen   +12 more
wiley   +1 more source

Labeless Immunosensor Assay for Fluoroquinolone Antibiotics Based Upon an AC Impedance Protocol. [PDF]

, 2007
This paper describes the construction of a labeless immunosensor for the antibiotic ciprofloxacin and its interrogation using an AC impedance protocol. Commercial screen-printed carbon electrodes were used as the basis for the sensor.
Sanchez-Baeza, Francisco, Millner, P. A., Garifallou, Goulielmos-Zois, Gibson, Timothy D., Sánchez Baeza, Francisco J., Higson, Seamus P. J., Pinacho, Daniel G., Tsekenis, G., Gibson, T. D., Davis, F., Higson, S. P. J., Marco, M-Pilar, Garifallou, G. Z., Millner, Paul A., Marco, María Pilar, Davis, Frank, Tsekenis, Georgios   +16 more
core   +1 more source

A New Type of Modified Brassinosteroids for Enzyme-linked Immunosorbent Assay

Natural Product Communications, 2008
New modified brassinosteroids (BS) with a full set of specific functional groups and with an additional one at C-26 have been synthesized and used as haptens for enzyme-linked immunosorbent assay. The haptens were conjugated to bovine serum albumin (BSA)
Vladimir Khripach, Vladimir Zhabinskii, Alexey Antonchick, Raissa Litvinovskaya, Svetlana Drach, Oleg Sviridov, Andrey Pryadko, Tatyana Novik, Vitaliy Matveentsev, Bernd Schneider   +9 more
doaj   +1 more source

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

Advanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang, Mengyu Zhang, Weipeng Gong, Jiaxuan Wu, Junping Zhang, Wenxiu Zhang, Yue Liu, Kui Wang, Canhua Huang, Jun Zhou, Sijin Wu, Yan Li, Tianliang Li   +12 more
wiley   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

Decoding IGLL5 Mutation‐Mediated BCR Signaling: A Novel Mechanism of CD8+ T Cell Exhaustion and Ocular MALT Lymphoma Progression

Advanced Science, EarlyView.
OAML harbors recurrent IGLL5 mutations that reinforce CD79A/CD79B‐associated BCR signaling. Mechanistic analysis of the S47G and A54G variants reveals induction of CXCL10/CXCL11, enhanced CD8+ T‐cell recruitment, and exhaustion‐associated dysfunction, supporting an immune‐tolerant niche.
Andi Zhao, Haoyu Wei, Chenyu Zhou, Xinping Sun, Shuyan Da, Haiyu Liu, Zijin Wang, Hui Zhu, Shiya Shen, Qing Shao, Qi Gong, Hu Liu, Xuejuan Chen   +12 more
wiley   +1 more source

Prevalence of Echinococcus spp. Infection Using Coproantigen ELISA among Canids of Moghan Plain, Iran [PDF]

Background: Echinococcosis is one of the most important helminthic zoonotic diseases in Iran. Intestinal Scraping Technique (IST), the traditional method for diagnosis of infection in definitive hosts, has many disadvantages including low susceptibility ...
محمودی, محمود, زارع بیدکی, مجید, نکویی, حسن, پیازک, نورائر, موبدی, ایرج, صادقیه اهری, سعید, حبیب زاده, شهرام, کیا, عشرت بیگم, نداف, سعیدرضا, سیاوشی, محمد رضا   +9 more
core  

Light‐Activatable Nitric Oxide Release via Intramolecular Electron Transfer for Tumor Pyroptosis Induction

Advanced Science, EarlyView.
This work proposes a novel strategy to fabricate unimolecular pyroptosis photoinitiators activated by deep‐red light at low light doses. It relies on a photosensitization mechanism to trigger nitric oxide (NO) release from benzisothiadiazole‐based N‐nitrosanilines without modification of nitro moieties, thereby boosting pyroptosis‐mediated ...
Chuangxin Zhang, Ruipeng Li, Yunxia Wang, Feng Liu, Liheng Feng   +4 more
wiley   +1 more source