A theranostic nanoplatform is formulated with NIR‐II emissive lipophilic cyanine dye IRC18 to intercalate into genetically engineered IL12/CSF1R‐macrophage membrane‐liposome hybrid nanovesicles, which assists to achieve blood–brain barrier crossing, glioblastoma targeting, NIR‐II fluorescence imaging, image‐guided membrane‐targeted mild photothermal ...
Pengfei Chen+10 more
wiley +1 more source
Utility of Polymerase Chain Reaction, Enzyme-linked Immunosorbent Assay, and Gene Sequencing in Detecting Orientia tsutsugamushi Infection Among Pediatric Acute Encephalitis Syndrome Cases in Northern India. [PDF]
Mishra H+4 more
europepmc +1 more source
The study develops engineered exosomes (EmDEX@GA) for locoregional immunomodulation of tumor‐draining lymph node (TDLN). EmDEX@GA can actively target to TDLN and remodel its immunosuppressive microenvironment through the synergistic effects of PD‐1/PD‐L1 blockade and STING pathway activation, subsequently enhance anti‐tumor immunity and suppress tumor ...
Yizhen Wang+12 more
wiley +1 more source
Measurement of Anti-TNF Biologics in Serum Samples of Pediatric Patients: Comparison of Enzyme-Linked Immunosorbent Assay (ELISA) with a Rapid and Automated Fluorescence-Based Lateral Flow Immunoassay. [PDF]
Rossi C+14 more
europepmc +1 more source
Diagnosis of Fasciola sp. infections in cattle by enzyme-linked immunosorbent assay.
Tadashi Itagaki+6 more
openalex +2 more sources
Tissue transglutaminase autoantibody enzyme-linked immunosorbent assay in detecting celiac disease.
S. Sulkanen+8 more
semanticscholar +1 more source
A CTGF‐LYTAC nanoplatform is developed to selectively degrade connective tissue growth factor (CTGF) in triple‐negative breast cancer (TNBC), inhibiting TGF‐β signaling and cell interactions in the tumor microenvironment (TME). This strategy effectively suppresses tumor growth and metastasis, outperforming antibody‐based therapy.
Jia‐Yi Lin+11 more
wiley +1 more source
Development and Application of an Indirect Enzyme-Linked Immunosorbent Assay Based on a Recombinant Matrix Protein for the Serological Study of Porcine Deltacoronavirus in Mexican Pigs. [PDF]
Castañeda Montes FJ+4 more
europepmc +1 more source
This study uncovers that CD38high monocytes discriminate sepsis and sterile inflammation and are associated with 28‐day mortality in bacterial sepsis. Targeting CD38 therapy reduces inflammatory response in monocytes and in sepsis mice model. Mechanistically, CD38‐HIF‐1α/glycolysis/MGO loop exacerbates sepsis‐induced immune dysregulation.
Ning Hua+19 more
wiley +1 more source