Results 101 to 110 of about 6,233,293 (384)

Purification and properties of a HeLa cell enzyme able to remove the 5'- terminal protein from poliovirus RNA [PDF]

, 1980
Using a rapid phenol extraction assay, an enzyme was purified from uninfected HeLa cells that can cleave the 5'-terminal protein (VPg) from poliovirus RNA. Both cytoplasmic and nuclear extracts had enzymes with similar behavior.
Ambros, Victor, Baltimore, David
core  

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

Stoichiometry of soil enzyme activity at global scale.

Ecology Letters, 2008
Extracellular enzymes are the proximate agents of organic matter decomposition and measures of these activities can be used as indicators of microbial nutrient demand.
R. Sinsabaugh, C. Lauber, M. Weintraub, Bony Ahmed, S. Allison, C. Crenshaw, Alexandra R Contosta, D. Cusack, S. Frey, M. E. Gallo, T. B. Gartner, S. Hobbie, K. Holland, B. Keeler, J. Powers, Martina Štursová, C. Takacs-Vesbach, M. Waldrop, M. Wallenstein, D. Zak, L. Zeglin   +20 more
semanticscholar   +1 more source

Nerve Agent Hydrolysis Activity Designed into a Human Drug Metabolism Enzyme [PDF]

, 2010
Organophosphorus (OP) nerve agents are potent suicide inhibitors of the essential neurotransmitter-regulating enzyme acetylcholinesterase. Due to their acute toxicity, there is significant interest in developing effective countermeasures to OP ...
Andrew C. Hemmert, C. Linn Cadieux, Carol C. Edwards, Douglas M. Cerasoli, Fernando Rodrigues-Lima, John R. Cashman, Jonathan S. Edwards, Lyudmila Tsurkan, Matthew R. Redinbo, Monika Wierdl, Philip M. Potter, Roberto A. Chica, Shane A. Kasten, Stephen L. Mayo, Steven M. Lewis, Tamara C. Otto   +15 more
core   +6 more sources

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Scouting Enzyme Behavior

, 2002
Experimental exploration of enzymatic response in a multi-dimensional context faces the challenge of an explosive number of possible milieu conditions.
Colombano, S., Matsumaru, N., Zauner, K.-P.   +2 more
core  

Principal basis for enzyme power [PDF]

, 2008
The reaction rate enhancement that enzymes produce had not been fully appreciated. The object of the article is to present the mechanism of the enormous catalytic power of the enzymes.
Alexander G. Foigel
core   +1 more source

Cloning, preparation and preliminary crystallographic studies of penicillin V acylase autoproteolytic processing mutants [PDF]

, 2005
The crystallization of three catalytically inactive mutants of penicillin Vacylase (PVA) from Bacillus sphaericus in precursor and processed forms is reported.
Brannigan, J A, Chandra, P M, Dodson, G G, Prabhune, A, Pundle, A, Suresh, C G, Turkenburg, J P   +6 more
core   +2 more sources

An enzyme in disguise [PDF]

IUCrJ, 2020
The enzyme carbonic anhydrase binds its zinc ion by three histidine residues in a similar manner to the way copper is bound to nitrite reductase. This remote similarity has now been shown to be real [Andring et al. (2020). IUCrJ, 7, 287-293]. A carbonic anhydrase with two bound copper ions is also a nitrite reductase.
openaire   +4 more sources

Can we always sweep the details of RNA-processing under the carpet?

, 2013
RNA molecules follow a succession of enzyme-mediated processing steps from transcription until maturation. The participating enzymes, for example the spliceosome for mRNAs and Drosha and Dicer for microRNAs, are also produced in the cell and their copy ...
Berg, Johannes, de Meaux, Juliette, Klironomos, Filippos D.   +2 more
core   +1 more source