Results 121 to 130 of about 6,233,293 (384)

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

Enzyme‐enzyme interactions and their metabolic role

open access: yesFEBS Letters, 1990
There are continuing reports on the existence of complexes of sequential metabolic enzymes. New techniques for their detection have been described and include affinity electrophoresis and the use of anti‐idiotypic antibodies. Channeling of substrates has been reported for several systems as well as direct substrate transfer through dynamic enzyme ...
Paul A. Srere, Judit Ovádi
openaire   +2 more sources

EKSTRAKSI ENZIM PAPAIN GETAH BUAH PEPAYA UNTUK PROSES \ud DEPROTEINASI PADA PEMBUATAN KITIN DARI KULIT UDANG WINDU \ud DAN APLIKASINYA SEBAGAI BAHAN PENJERNIH SARI BUAH SIRSAK [PDF]

open access: yes, 2009
Papaya can produce enzyme that often called the enzyme papain. Usually, Enzyme is found in the resin or fruit that is still young. Papaya resin (papain) contains quite a variety of enzyme that is proteolotik (The protein).
PUSPANINGRUM, LILIANTI
core  

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

Umami and saltiness enhancements of textured pea proteins by combining protease- and glutaminase-catalyzed reactions

open access: yesCurrent Research in Food Science
Plant-based meat analogs (PBMAs) have attracted attention owing to their various advantages, however, their taste limits their application, requiring improvement of the umami and saltiness levels while meeting clean-label requirements.
Kiyota Sakai   +4 more
doaj  

Review of the Structural Characteristics and Biological Activities of Tricholoma Secondary Metabolites (2018–2023)

open access: yesMolecules
Tricholoma are significant medicinal and edible mushrooms within Basidiomycota. Known for their various medicinal properties such as anti-tumor, immune regulation, and antioxidant effects, they are regarded worldwide as health foods of the 21st century ...
Meili Zhao   +4 more
doaj   +1 more source

How an Enzyme Can Be a Non-Enzyme [PDF]

open access: yesStructure, 2004
AbstractThe crystal structure of the endonuclease, ribonuclease III, in complex with a double-stranded RNA fragment reveals the mechanism that allows for switching between two functional forms of the enzyme.
openaire   +4 more sources

Absolute Metabolite Concentrations and Implied Enzyme Active Site Occupancy in Escherichia coli

open access: yesNature Chemical Biology, 2009
Absolute metabolite concentrations are critical to a quantitative understanding of cellular metabolism, as concentrations impact both the free energies and rates of metabolic reactions.
Bryson D. Bennett   +5 more
semanticscholar   +1 more source

Actinidin : the predominant protease in kiwifruit : a thesis presented in partial fulfilment of the requirements for the degree of Master of Philosophy in Food technology at Massey University, Manawatū, New Zealand [PDF]

open access: yes, 2016
Kiwifruit protein (actinidin) has been widely known as a protease. Kiwifruit protein has the potential of utilization in food industry as an enzyme that aids food digestion.
Chao, Dongfang
core  

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