Results 131 to 140 of about 4,423,700 (359)

A multimodal model for protein function prediction

open access: yesScientific Reports
Protein function, which is determined by sequence, structure, and other characteristics, plays a crucial role in an organism’s performance. Existing protein function prediction methods mainly rely on sequence data and often ignore structural properties ...
Yu Mao   +6 more
doaj   +1 more source

Ueber die Enzyme [PDF]

open access: green, 1894
Claudio Fermi, Leone Pernossi
openalex   +1 more source

Hypomethylating agents increase L1 retroelement expression without inducing novel insertions in myeloid malignancies

open access: yesMolecular Oncology, EarlyView.
We investigated whether hypomethylating agents (HMAs) used in myeloid malignancies induce somatic retrotransposition. Our findings indicate that HMA treatment increases L1‐encoded protein expression but does not lead to detectable de novo retrotransposition events in either patient samples or cell lines.
Šárka Pavlová   +14 more
wiley   +1 more source

A Novel Angiotensin-Converting Enzyme–Related Carboxypeptidase (ACE2) Converts Angiotensin I to Angiotensin 1-9

open access: yesCirculation Research, 2000
M. Donoghue   +11 more
semanticscholar   +1 more source

The tumor–microbe connection

open access: yesMolecular Oncology, EarlyView.
Tumor‐associated bacteria (TAB) dynamically influence cancer biology by modulating tumor progression, metastatic spread, and therapeutic efficacy. Their presence redefines the tumor microenvironment (TME) as a microbial–host interface, yet mechanistic insights remain limited. Understanding TAB colonization routes, functional impacts, and crosstalk with
Gerlanda Vella, Maria Rescigno
wiley   +1 more source

Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker.

open access: yesJournal of Investigative Dermatology, 1982
P. Bradley   +3 more
semanticscholar   +1 more source

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

open access: yesMolecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin   +10 more
wiley   +1 more source

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