Results 241 to 250 of about 6,423,279 (401)

Incorporation of an unnatural amino acid in the active site of porcine pancreatic phospholipase A₂. Substitution of histidine by l,2,4-triazole-3-alanine yields an enzyme with high activity at acidic pH [PDF]

, 1996
Sigrid H.W. Beiboer, Bert van den Berg, Niek Dekker, Ruud C. Cox, Hubertus M. Verheij   +4 more
openalex   +1 more source

The Roles of Enzymes as Dietary Additives in Ruminant Diets: A Meta-Analysis. [PDF]

Animals (Basel)
Ramdani D, Rahmatillah RS, Yanza YR, Jayanegara A, Wathoni N, Chaudhry AS.   +5 more
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

The Combination of Green Tea Extract and Eriodictyol Inhibited High-Fat/High-Sucrose Diet-Induced Cholesterol Upregulation Is Accompanied by Suppression of Cholesterol Synthesis Enzymes

, 2016
Mai Yamashita, Motofumi Kumazoe, Yuki Nakamura, Yeong Seon Won, Jae‐Hoon Bae, Shuya Yamashita, Hirofumi Tachibana   +6 more
openalex   +2 more sources

Safety evaluation of the food enzyme cellulase from the genetically modified <i>Trichoderma reesei</i> strain AR-715. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Van Loveren H, Vernis L, Lunardi S, Andryszkiewicz M, Cavanna D, Criado A, Fernàndez-Fraguas C, Liu Y.   +18 more
europepmc   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Exploring metabolic reprogramming in esophageal cancer: the role of key enzymes in glucose, amino acid, and nucleotide pathways and targeted therapies

Xue-Man Dong, Lin Chen, Yuxin Xu, Pu Wu, Tian Xie, Zhao-Qian Liu   +5 more
openalex   +1 more source

Time of Initiating Enzyme Replacement Therapy Affects Immune Abnormalities and Disease Severity in Patients with Gaucher Disease

, 2016
Renuka P. Limgala, Chidima Ioanou, Matthew Plassmeyer, Mark Ryherd, Lina Kozhaya, Lauren Austin, Cem Abidoglu, Derya Unutmaz, Oral Alpan, Özlem Göker-Alpan   +9 more
openalex   +2 more sources

A comparative study of two retaining enzymes of Trichoderma reesei: transglycosylation of oligosaccharides catalysed by the cellobiohydrolase I, Cel7A, and the β‐mannanase, Man5A [PDF]

, 1999
Vesa Harjunpää, Jari Helin, Anu Koivula, Matti Siika‐aho, Torbjörn Drakenberg   +4 more
openalex   +1 more source

The Performance of Protein Meal from <i>Hermetia illucens</i> Larvae in Hetero-Clarias Hybrid Farming. [PDF]

Insects
Georgescu B, Georgescu C, Păpuc T, Vasiu M, Struți D, Boaru A.   +5 more
europepmc   +1 more source