Results 181 to 190 of about 5,306,282 (389)

Inhibition of a viral enzyme by a small-molecule dimer disruptor. [PDF]

, 2009
We identified small-molecule dimer disruptors that inhibit an essential dimeric protease of human Kaposi's sarcoma-associated herpesvirus (KSHV) by screening an alpha-helical mimetic library.
Arnold, Leggy A, Craik, Charles S, Guy, R Kiplin, Lazic, Ana, Lee, Gregory M, Roels, Christina M, Shahian, Tina, Velusamy, Priya   +7 more
core  

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

Assaying Sterile Concentrated Milk for Native Proteolytic Enzymes

, 1964
S. Nakai, H.K. Wilson, E.O. Herreid
openalex   +1 more source

Antibody Assays for Varicella-Zoster Virus: Comparison of Enzyme Immunoassay with Neutralization, Immune Adherence Hemagglutination, and Complement Fixation [PDF]

, 1978
Bagher Forghani, Nathalie J. Schmidt, Juanita Dennis   +2 more
openalex   +1 more source

Construction of hyperthermostable d‐allulose 3‐epimerase from Arthrobacter globiformis M30 using the sequence information from Arthrobacter psychrolactophilus

FEBS Open Bio, EarlyView.
d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada, Kouhei Ohtani, Pushpa Kiran Gullapalli, Kazuhiko Ishikawa   +3 more
wiley   +1 more source

Detection of antibodies to Mycoplasma pulmonis by an enzyme-linked immunosorbent assay [PDF]

, 1978
S. Horowitz, Gail H. Cassell
openalex   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Assay of proteolytic enzyme(s) from Neurospora crassa

, 1965
R. B. Drysdale, Marguerite Fling
openalex   +2 more sources

Solid-phase enzyme-linked immunosorbent assay for detection of hepatitis A-specific immunoglobulin M [PDF]

, 1979
Stephen Locarnini, A G Coulepis, Ann Stratton, J. Kaldor, Ian D. Gust   +4 more
openalex   +1 more source

Earthing effects on mitochondrial function: ATP production and ROS generation

FEBS Open Bio, EarlyView.
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley   +1 more source