Results 261 to 270 of about 2,214,190 (390)
Viridicatol from the Deep‐Sea‐Derived Fungus Alleviates Bone Loss by Targeting the Wnt/SHN3 Pathway
Advanced Science, EarlyView.Viridicatol (VDC), isolated from the deep‐sea‐derived fungus, enhances osteogenesis in vitro and in vivo by targeting Wnt/SHN3 signaling pathway. It can be delivered via engineered nanovesicles to mitigate bone loss of osteoporosis, fracture repair, and osteogenesis imperfecta.
Chun‐Lan Xie +10 more
wiley +1 more source
The immobilization of microbial cells, subcellular organelles, and enzymes in calcium alginate gels [PDF]
, 2000 M. Kierstan, C. Bucke
openalex +1 more source
Metal–Organic Frameworks: Unlocking New Frontiers in Cardiovascular Diagnosis and Therapy
Advanced Science, EarlyView.Metal–organic frameworks (MOFs), are composed of metal ions and bridging organic ligands, are recognized as an excellent platform for host‐gust chemistry. Its rich structural composition, modifiable sites, and multilevel pore distribution can provide delivery and release of signaling molecules, probes, and therapeutic drugs, which exhibit great medical
Qilu Wu +6 more
wiley +1 more source
Region-Directed Enzyme Immobilization through Engineering Protein Surface with Histidine Clusters. [PDF]
ACS Appl Mater InterfacesZeballos N +7 more
europepmc +1 more source
Multifunctional Conductive Nanofibers for Self‐Powered Glucose Biosensors
Advanced Science, EarlyView.This work develops a novel self‐powered glucose biosensor using polycaprolactone/polypyrrole/graphene oxide (PCL/PPy/GO) nanofibers integrated with a triboelectric nanogenerator. The system achieves high glucose detection sensitivity and generates 63 V from motion, combining robust mechanical strength with eco‐friendly energy harvesting.
Seda Gungordu Er +7 more
wiley +1 more source
RACK7 Interacts with PRC2 Complex to Regulate Astrocyte Development
Advanced Science, EarlyView.The study investigates the role of RACK7 in brain development using a conditional knockout mouse model. RACK7 deficiency results in developmental defects and abnormal astrocyte development by disrupting H3K27me3 chromatin binding. The underlying mechanism involves RACK7 interacting with the PRC2 complex to regulate the genomic localization of SUZ12 and
Fangfang Jiao +9 more
wiley +1 more source
DNA Molecular Computing with Weighted Signal Amplification for Cancer miRNA Biomarker Diagnostics
Advanced Science, EarlyView.A molecular computing approach is presented with weighted signal amplification. Polymerase‐mediated strand displacement is employed to assign weights to target miRNAs, reflecting the miRNAs’ diagnostic values, followed by amplification of the weighted signals using localized DNA catalytic hairpin assembly.
Hongyang Zhao +6 more
wiley +1 more source