Creating a non-native bio-amidation activity in asparagine synthetase <i>via</i> biosensor-guided directed evolution for the synthesis of (<i>S</i>)-2-aminobutyramide. [PDF]
Lai Q +7 more
europepmc +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Simultaneous GCN4 co-expression and promoter optimization enhance glucose oxidase production in <i>Pichia pastoris</i>. [PDF]
Ghafari N +6 more
europepmc +1 more source
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk +10 more
wiley +1 more source
Serum aromatic l-amino acid decarboxylase activity as a biomarker for prodromal and manifest Parkinson's disease. [PDF]
Beckers M +6 more
europepmc +1 more source
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao +5 more
wiley +1 more source
The Role of Cytochrome P450 Holoenzyme Metabolism in the Origin of Neuropathologies. [PDF]
Štambuk S.
europepmc +1 more source
A universal medium bridging the shake-flask to fermenter gap in <i>Pichia pastoris</i> for enhanced zearalenone lactonase production. [PDF]
Liu H +5 more
europepmc +1 more source
Comprehensive Genome Identification of the <i>PHD</i> Gene Family in <i>Panax ginseng</i> and Expression Analysis of <i>PgPHD</i> Genes in Response to MeJA. [PDF]
Xu Z +9 more
europepmc +1 more source

