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Characterization of novel cellobiose 2-epimerases from Teredinibacter Haidensis and Cellvibrio Japonicus. [PDF]
BMC BiotechnolLiu Y, Lutz-Wahl S, Fischer L.
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Loss of the ER-cargo protein CLN8 increases severity of acute pancreatitis and upregulates ER-stress and ER-phagy. [PDF]
Mol BiomedZierke L +9 more
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Valine overproduction in <i>Methanothermobacter marburgensis</i> with temperature-induced promoter system and allosteric resistant acetolactate synthase variants. [PDF]
Metab Eng CommunUnger F +7 more
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Enzyme induction and inhibition
Pharmacology & Therapeutics, 1990The rate and extent of drug metabolism significantly influences drug effect. Enzyme induction by increasing the metabolism of drugs may result in important drug interactions. Other implications of enzyme induction include alterations in the metabolism of endogenous substrates, vitamins and activity of extrahepatic enzyme systems. Similarly a wide range
M, Barry, J, Feely
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Toxicologic Pathology, 2010
Hepatic enzyme induction is generally an adaptive response associated with increases in liver weight, induction of gene expression, and morphological changes in hepatocytes. The additive growth and functional demands that initiated the response to hepatic enzyme induction cover a wide range of stimuli including pregnancy and lactation, hormonal ...
Robert R, Maronpot +7 more
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Hepatic enzyme induction is generally an adaptive response associated with increases in liver weight, induction of gene expression, and morphological changes in hepatocytes. The additive growth and functional demands that initiated the response to hepatic enzyme induction cover a wide range of stimuli including pregnancy and lactation, hormonal ...
Robert R, Maronpot +7 more
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Journal of Steroid Biochemistry, 1983
The injection of estrogen into an immature or ovariectomized rat results in an increase in the specific activities of many uterine enzymes which can be detected, usually, within hours to days. The recent identification of the "estrogen-induced protein" as the brain type isozyme of creatine kinase (CKBB), provided an easily measurable enzyme marker, the
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The injection of estrogen into an immature or ovariectomized rat results in an increase in the specific activities of many uterine enzymes which can be detected, usually, within hours to days. The recent identification of the "estrogen-induced protein" as the brain type isozyme of creatine kinase (CKBB), provided an easily measurable enzyme marker, the
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Trans-synaptic enzyme induction
Life Sciences, 1974Publisher Summary This chapter discusses the trans-synaptic enzyme induction. The increase in tyrosine hydroxylase synthesis is not a manifestation of a general increase in protein synthesis in the adrenergic neuron because under experimental conditions leading to a 2- to 3-fold increase in tyrosine hydroxylase activity, there was no detectable ...
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Clinical Implications of Enzyme Induction and Enzyme Inhibition
Clinical Pharmacokinetics, 1981The pharmacological effect of a drug is partly dependent upon its concentration at its site of action, which in turn is partly dependent upon its rate of elimination. The rate of elimination of many lipophilic drugs is governed by the activity of the hepatic microsomal mixed-function oxidases.
B K, Park, A M, Breckenridge
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