Results 61 to 70 of about 680,545 (215)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Production and Expression Optimization of Heterologous Serratiopeptidase

Iranian Journal of Public Health, 2020
Background: Serratiopeptidase is a bacterial metalloprotease, which is useful for the treatment of pain and inflammation. It breaks down fibrin, thins the fluids formed during inflammation and acts as an anti-biofilm agent.
Maryam ROUHANI, Vahideh VALIZADEH, Sara MOLASALEHI, Dariush NOROUZIAN   +3 more
doaj  

Induction of Herbicide Detoxifying Enzyme in Maize by Chiral 3-Dichloroacetyl Oxazolidine

Journal of Agricultural Sciences, 2018
Safeners are important tools used to ensure to safe useof herbicide. The aim of this paper is to evaluate the protective effect of four safeners (R-28725, 3-dichloroacetyl oxazolidine and its two optical isomers) and investigate the mechanism of ...
Fei Yei, Li-xia Zhao, Shuang Gao, Qing-rui Wang, Ying Fu, Chun-yan Lı   +5 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Polyphenol Oxidase Induction in Lulo Fruits (Solanum quitoense) Infected by Colletotrichum acutatum

Acta Biológica Colombiana, 2007
Polyphenol oxidase (PFO) activity induction was evaluated in lulo fruits to determine the role of this enzyme in resistance responses towards the pathogen Colletotrichum acutatum which causes anthracnose disease. We studied the experimental conditions to
Obradith Caicedo O., Blanca L. Higuera
doaj  

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Cloning and Optimization of Formate Dehydrogenase Gene Expression in E. COLI [PDF]

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd
Introduction: The increase in greenhouse gas levels and the gradual warming of the earth have garnered worldwide interest. The enzyme formate-dehydrogenase can reduce CO2 by converting it into formate, which is subsequently converted into methanol by the
Mohammad Reza Hajizadeh, Amir Mohammad Jafari Kakhki, Mahboubeh Nabavinia, Maryam Sadat Nabavinia   +3 more
doaj  

Effects of Different Inducers on Higher Alcohol Dehydrogenase from Galactomyces geotrichum

Shipin gongye ke-ji
The inducers of the chemical or physical factors could affect the gene expression and transcription of strain directly or indirectly. In order to explore the inductive effect of higher alcohol on Galactomyces geotrichum, the G.
Jing ZHU, Xiaocong YANG, Yalan CHEN, Haibo LIU, Long CHEN, Xueke ZHENG, Junling SHI   +6 more
doaj   +1 more source