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Novel Perceptions on Chemical Profile and Biopharmaceutical Properties of Mentha spicata Extracts: Adding Missing Pieces to the Scientific Puzzle

Plants, 2022
Mentha spicata is one of the most popular species in the genus, and it is of great interest as a gastrointestinal and sedative agent in the folk medicine system. In this study, different M.
Gokhan Zengin, Gunes Ak, Ramazan Ceylan, Sengul Uysal, Eulogio Llorent-Martínez, Simonetta Cristina Di Simone, Monica Rapino, Alessandra Acquaviva, Maria Loreta Libero, Annalisa Chiavaroli, Lucia Recinella, Sheila Leone, Luigi Brunetti, Amelia Cataldi, Giustino Orlando, Luigi Menghini, Claudio Ferrante, Marwa Balaha, Viviana di Giacomo   +18 more
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Research on Diffusible Signal Factor-Mediated Quorum Sensing in Xanthomonas: A Mini-Review

Molecules, 2023
Xanthomonas spp. are important plant pathogens that seriously endanger crop yields and food security. RpfF is a key enzyme that is involved in the synthesis of diffusible signal factor (DSF) signals and predominates in the signaling pathway regulating ...
Yu-Mei Feng, Zhou-Qing Long, Hong-Mei Xiang, Jun-Ning Ran, Xiang Zhou, Song Yang   +5 more
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Biochemical characterization and identification of ferulenol and embelin as potent inhibitors of malate:quinone oxidoreductase from Campylobacter jejuni

Frontiers in Molecular Biosciences, 2023
Campylobacter jejuni infection poses a serious global threat to public health. The increasing incidence and antibiotic resistance of this bacterial infection have necessitated the adoption of various strategies to curb this trend, primarily through ...
Augustin Tshibaka Kabongo, Augustin Tshibaka Kabongo, Augustin Tshibaka Kabongo, Rajib Acharjee, Rajib Acharjee, Rajib Acharjee, Takaya Sakura, Takaya Sakura, Gloria Mavinga Bundutidi, Gloria Mavinga Bundutidi, Gloria Mavinga Bundutidi, Gloria Mavinga Bundutidi, Endah Dwi Hartuti, Endah Dwi Hartuti, Endah Dwi Hartuti, Cadi Davies, Ozan Gundogdu, Kiyoshi Kita, Kiyoshi Kita, Kiyoshi Kita, Tomoo Shiba, Daniel Ken Inaoka, Daniel Ken Inaoka, Daniel Ken Inaoka   +23 more
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Nanozymes as Enzyme Inhibitors

International Journal of Nanomedicine, 2021
Nanozyme is a type of nanomaterial with intrinsic enzyme-like activity. Following the discovery of nanozymes in 2007, nanozyme technology has become an emerging field bridging nanotechnology and biology, attracting research from multi-disciplinary areas focused on the design and synthesis of catalytically active nanozymes.
Yaling Huang, Jian Jiang, Juqun Xi, Jie Chen, Yanqiu Wang   +4 more
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Synthesis of Benzylidene Analogs of Oleanolic Acid as Potential α-Glucosidase and α-Amylase Inhibitors

Frontiers in Chemistry, 2022
A series of benzylidene analogs of oleanolic acid 4a∼4s were synthesized and assessed for their α-glucosidase and α-amylase inhibitory activities. The results presented that all synthesized analogs exhibited excellent-to-moderate inhibitory effects on α ...
Jun-Jie Ke, Jing Lin, Xin Zhang, Xiao-Zheng Wu, Ying-Ying Zheng, Chun-Mei Hu, Yu Kang, Kun Zhang, Zhuang Xiong, Zhi-Qiang Ma   +9 more
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Tyrosine Hydroxylase and DOPA Decarboxylase Are Associated With Pupal Melanization During Larval–Pupal Transformation in Antheraea pernyi

Frontiers in Physiology, 2022
In insects, melanism plays important roles in defense, immunoreactions, and body color. The underlying molecular mechanisms of melanism in different insects are diverse and remain elusive.
Qi Wang, Liang Zhong, Yong Wang, Shengwei Zheng, Yumeng Bian, Junhao Du, Ruisheng Yang, Wei Liu, Li Qin   +8 more
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Synthesis and Evaluation of Coumarin-Chalcone Derivatives as α-Glucosidase Inhibitors

Frontiers in Chemistry, 2022
Coumarin and chalcone, two important kinds of natural product skeletons, both exhibit α-glucosidase inhibitory activity. In this work, coumarin-chalcone derivatives 3 (a∼v) were synthesized, and their α-glucosidase inhibitory activity was screened.
Chun-Mei Hu, Yong-Xin Luo, Wen-Jing Wang, Jian-Ping Li, Meng-Yue Li, Yu-Fei Zhang, Di Xiao, Li Lu, Zhuang Xiong, Na Feng, Chen Li   +10 more
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Screening of Tyrosinase, Xanthine Oxidase, and α-Glucosidase Inhibitors from Polygoni Cuspidati Rhizoma et Radix by Ultrafiltration and HPLC Analysis

Molecules, 2023
Polygoni Cuspidati Rhizoma et Radix (PCR), the rhizome and root of Polygonum cuspidatum Sieb. et Zucc., has been used as an herbal medicine for a long time. In this study, the ultrafiltration combined with high performance liquid chromatography (UF-HPLC)
Jing Chen, Qi Huang, Zhuobin He, Guoying Tan, Yuansheng Zou, Juying Xie, Zhengming Qian   +6 more
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Cryptic Metabolites from Marine-Derived Microorganisms Using OSMAC and Epigenetic Approaches

Marine Drugs, 2022
Marine microorganisms have proven to be a source of new natural products with a wide spectrum of biological activities relevant in different industrial sectors.
Cristina Pinedo-Rivilla, Josefina Aleu, Rosa Durán-Patrón   +2 more
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Guianensin, a Simulium guianense salivary protein, has broad anti-hemostatic and anti-inflammatory properties

Frontiers in Immunology, 2023
BackgroundSalivary glands from blood-feeding arthropods secrete several molecules that inhibit mammalian hemostasis and facilitate blood feeding and pathogen transmission.
Paola Carolina Valenzuela-Leon, Andrezza Campos Chagas, Ines Martin-Martin, Adeline E. Williams, Markus Berger, Gaurav Shrivastava, Andrew S. Paige, Michalis Kotsyfakis, Michalis Kotsyfakis, Lucas Tirloni, Eric Calvo   +10 more
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