Results 141 to 150 of about 870,116 (308)

Repurposing nirogacestat, a gamma secretase enzyme inhibitor in desmoid tumors. [PDF]

Future Oncol
Tansir G, Rastogi S, Gounder MM.
europepmc   +1 more source

Influence of Type of Questionnaire on the Prevalence of Coughing in Patients Taking Angiotensin Converting Enzyme Inhibitors(ACEI).

, 1996
Nobuyuki Goto, Masaki Shirahase, Hisao HATTA, Mikio Masada, Jong‐Dae Lee, Akiyoshi Tsubokawa, Hiromasa Shimizu, Takanori Ueda, Tõru Nakamura, SHIKIFUMI KITAZAWA   +9 more
openalex   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Risk factors for angiotensin converting enzyme inhibitor angioedema in a South African population. [PDF]

Front Allergy
Day C, Mapahla L, Ribeiro M, Deetlefs M, McDougall C, Engelbrecht A, Jones E, Pedretti S, Peter J.   +8 more
europepmc   +1 more source

Modelling studies of the active site of human sorbitol dehydrogenase: an approach to structure-based inhibitor design of the enzyme

, 2001
Connie Darmanin, Ossama El‐Kabbani
openalex   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Selection for Postponed Senescence in Drosophila melanogaster Reveals Distinct Metabolic Aging Trajectories Modifiable by the Angiotensin-Converting Enzyme Inhibitor Lisinopril. [PDF]

Aging Cell
Vecchié D, Anholt RRH, Mackay TFC, De Luca M.   +3 more
europepmc   +1 more source

The influence of non-specific serum inhibitors in enzyme immune assay used for detection of anti-influenza antibodies

, 2002
Fernando Couto Motta, J. Couceiro, Maria H. Silva   +2 more
openalex   +1 more source

Individualised therapy of angiotensin converting enzyme (ACE) inhibitors in stable coronary artery disease: overview of the primary results of the PERindopril GENEtic association (PERGENE) study [PDF]

, 2011
Jasper J. Brugts, Moniek P.M. de Maat, A.H. Jan Danser, Eric Boersma, Maarten L. Simoons   +4 more
openalex   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source