Results 141 to 150 of about 1,349,855 (362)

Interaction of Human Sperm Acrosomal Proteinase with Human seminal Plasma Proteinase Inhibitors [PDF]

, 1973
Fink, Edwin, Fritz, Hans, Jaumann, Eugen, Schumacher, D. F. B., Zaneveld, L. J. D.   +4 more
core   +1 more source

The Coenzyme Requirement and Enzyme Inhibitors of Pineapple Indoleacetic Acid Oxidase

, 1958
Willis A. Gortner, Martha Kent
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity

Molecular Oncology, EarlyView.
Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause, Rixa‐Mareike Köhn, Christian Ickes, Julia Lenger, Jonas Fischer, Sabrina Cappello, Ivan Bogeski   +6 more
wiley   +1 more source

Kallikrein inhibitors [PDF]

, 1979
Fink, Edwin, Fritz, Hans, Truscheit, Ernst   +2 more
core   +1 more source

The Impact of Inorganic Systems and Photoactive Metal Compounds on Cytochrome P450 Enzymes and Metabolism: From Induction to Inhibition

Biomolecules
While cytochrome P450 (CYP; P450) enzymes are commonly associated with the metabolism of organic xenobiotics and drugs or the biosynthesis of organic signaling molecules, they are also impacted by a variety of inorganic species.
Dmytro Havrylyuk, David K. Heidary, Edith C. Glazer   +2 more
doaj   +1 more source

INHIBITORS OF MILK-CURDLING ENZYMES

, 1934
Henry Tauber
openalex   +1 more source

Enzymes Produced by a Pseudomonas Species Which Inactivate Inhibitors of Certain Viral Hemagglutinins. I. Identification and Purification of a Proteinase and Phospholipase C [PDF]

, 1969
Nathalie J. Schmidt, Pinkie S. Gee, Juanita Dennis, Edwin H. Lennette   +3 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

ROLE OF ESTERATIC INHIBITION ON LOCALIZATION OF ESTERASE AND THE SIMULTANEOUS CYTOCHEMICAL DEMONSTRATION OF INHIBITOR SENSITIVE AND RESISTANT ENZYME SPECIES [PDF]

, 1961
Theodor K. Shnitka, Arnold M. Seligman
openalex   +1 more source