Results 211 to 220 of about 716,218 (261)

Enzyme kinetics in relation to enzyme inhibitors

Biochemical Pharmacology, 1973
Abstract A Large number of pharmacologically important compounds have been found to act as enzyme inhibitors and a kinetic study of the inhibitory process can provide important information on the potency of the compound and on its mode of interaction with the enzyme.
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Inhibitors of Kinin-Forming Enzymes

Agents and Actions, 1976
The typical trypsin-like protease in animals were plasmin, kallikrein, thrombin, factor X, XI, XII, cathepsin B, plasminogen tissue activator and urokinase, and so on. Among them plasmin and kallikrein have kinin-forming activity. A synthetic reversible inhibitor of plasmin, and anticoagulant factor of blood, has been extensively studied.
openaire   +2 more sources

Angiotensin-Converting Enzyme Inhibitors

Journal of Hypertension, 1991
The introduction of angiotensin-converting enzyme (ACE) inhibitors for the treatment of hypertension and heart failure is probably the most important advance in cardiovascular pharmacotherapy in the last few decades. Although the role of the renin-angiotensin system (RAS) in cardiovascular diseases had been investigated extensively for more than 70 yr,
Irene Gavras, Haralambos Gavras
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Angiotensin-converting enzyme inhibitors

2001
Publisher Summary Angiotensin-converting enzyme (ACE) inhibitors were first studied clinically in the 1970s. ACE inhibitors were discovered by taking advantage of previous basic research on the physiology of sodium, potassium, and water homeostasis and blood pressure regulation, in a reciprocal way ACE have also advanced research in this field, and ...
J, Menard, A A, Patchett
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Enzymes and Their Inhibitors

2004
Focusing on the development of enzyme inhibitors as therapeutic drugs, Enzymes and Their Inhibitors: Drug Development provides a concise overview of the chemistry of major types of enzymes and their inhibitors. The opening chapters introduce readers to the structure, functions, mechanisms, and kinetics of enzymes, including their use as disease ...
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Enzyme inhibitors in medicine

Natural Product Reports, 1989
C S, Walpole, R, Wrigglesworth
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Inhibitors of mitochondrial enzymes

Pharmacology & Therapeutics, 1979
J B, Clark, J M, Land
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Endogenous enzymes and enzyme inhibitors

2023
Christophe M. Courtin, Najwa Shufia Choliq, Mariette Bernard, Axelle Görtz, Gitte Devriese   +4 more
openaire   +1 more source

The Use of Enzyme Inhibitors in Drug Discovery: Current Strategies and Future Prospects

Current Enzyme Inhibition, 2023
Devender Pathak, Jeetendra Kumar Gupta, Kuldeep Singh   +2 more
exaly  

Angiotensin‐Converting Enzyme Inhibitors or Angiotensin Receptor Blockers Use and COVID‐19 Infection Among 824 650 Patients With Hypertension From a US Integrated Healthcare System

Journal of the American Heart Association, 2021
Michael Gould, Kristi Reynolds, John Sim   +2 more
exaly