Results 221 to 230 of about 5,633,974 (393)

7076 Inhibiting Oxidosqualene Cyclase, an Enzyme in the Cholesterol Biosynthetic Pathway, Suppresses Lung Metastasis of Triple-negative Breast Cancer Cells

Yayun Liang, Salman M. Hyder
openalex   +1 more source

Angiotensin converting enzyme inhibitors and angiotensin receptor blockers in hypertensive African Americans [PDF]

, 2003
P NARAYAN
openalex   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Under ONIOM Layers: Analysis of BCR-ABL Enzyme Inhibitors Through Bond-Critical Points and Natural Orbitals. [PDF]

Molecules
Rocha KML, Nascimento ÉCM, Martins JBL.
europepmc   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Angiotensin converting enzyme inhibitors (ACEIs) for anthracycline-induced cardiotoxicity: a systematic review and meta-analysis of randomized controlled trials. [PDF]

Ann Saudi Med
Safwan M, Bourgleh MS, AlShakaki H, Haider KH.   +3 more
europepmc   +1 more source

Proteinases and proteinase inhibitors in ejaculates of men with adnex affections [PDF]

, 1985
Brunner, H., Fink, Edwin, Friesen, A., Hofstetter, A., Jochum, Marianne, Krause, W., Rothauge, C. F., Schießler, Hans, Schill, W.-B., Weidner, W.   +9 more
core  

Renoprotective effect of combining pentoxifylline with angiotensin-converting enzyme inhibitor or angiotensin II receptor blocker in advanced chronic kidney disease

, 2014
Ping-Min Chen, Tai‐Shuan Lai, Ping‐Yu Chen, Chun‐Fu Lai, Vin‐Cent Wu, Wen‐Chih Chiang, Yung‐Ming Chen, Kwan‐Dun Wu, Tun‐Jun Tsai   +8 more
openalex   +2 more sources

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Computational-experimental integration identifies potent carbohydrate-hydrolyzing enzyme inhibitors from <i>Nardostachys jatamansi</i>: molecular docking, dynamics and pharmacokinetic predictions. [PDF]

Front Pharmacol
Iqbal MJ, Malik I, Bernal G, Salas-Burgos AM, Salazar LA.   +4 more
europepmc   +1 more source