Results 221 to 230 of about 5,417,177 (410)

Studies on Specific Enzyme Inhibitors

, 1964
D.W. Fanshier, L.K. Gottwald, É. Kun
openalex   +1 more source

Purification and Properties of the γ-Protein Specified by Bacteriophage λ: An Inhibitor of the Host RecBC Recombination Enzyme [PDF]

, 1973
Yoshiyuki Sakaki, Alexander E. Karu, Stuart Linn, Harrison Echols   +3 more
openalex   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source

Concerning a Crystalline Chymotryptic Inhibitor from Potatoes, and Its Binding Capacity for the Enzyme

, 1963
A.K. Balls, Clarence A. Ryan
openalex   +1 more source

alpha-N-Benzoylarginine-2-naphthylamide Hydrolase (Cathepsin B1 ?) from Rat Skin. II. Purification of the Enzyme and Demonstration of Two Inhibitors in the Skin. [PDF]

, 1975
M. Järvinen, V. K. Hopsu‐Havu, Mona Grönlund, Anna‐Britta Hörnfeldt, Rolf Servin, Hans Sternerup   +5 more
openalex   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Effects of α-difluoromethylornithine, an enzyme-activated irreversible inhibitor of ornithine decarboxylase, on testosterone-induced regeneration of prostate and seminal vesicle in castrated rats [PDF]

, 1979
Charles Danzin, Michel J. Jung, Nicole Claverie, Jeffrey Grove, Albert Sjoerdsma, Jan Koch‐Weser   +5 more
openalex   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Exploring the Potential of Pyridine Carboxylic Acid Isomers to Discover New Enzyme Inhibitors. [PDF]

Drug Des Devel Ther
Yaqoob S, Khan FA, Tanveer N, Ali S, Hameed A, El-Seedi H, Jiang ZH, Wang Y.   +7 more
europepmc   +1 more source

Machine Learning Approaches to Investigate the Structure-Activity Relationship of Angiotensin-Converting Enzyme Inhibitors. [PDF]

ACS Omega, 2023
Yu T, Nantasenamat C, Anuwongcharoen N, Piacham T.   +3 more
europepmc   +1 more source