Results 271 to 280 of about 689,457 (314)
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Food Chemistry, 1981
Abstract The range of proteins from plants which form reversible stoichiometric protein-protein complexes with enzymes, thus inhibiting their catalytic functions, is surveyed. Details of the biochemistry of the proteinase- and α-amylase inhibitors found in the important food crops such as the cereals, legumes and potatoes are given.
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Abstract The range of proteins from plants which form reversible stoichiometric protein-protein complexes with enzymes, thus inhibiting their catalytic functions, is surveyed. Details of the biochemistry of the proteinase- and α-amylase inhibitors found in the important food crops such as the cereals, legumes and potatoes are given.
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angiotensin converting enzyme inhibitors
2012More than 30 years since their discovery, angiotensin-converting enzyme (ACE) inhibitors still represent one of the most commonly prescribed medications for treating hypertension and one of the favored first-line agents, particularly in the presence of high-risk conditions, such as diabetes.
GENTILE, GIORGIO +4 more
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2010
Synthetic biomimetic compounds play crucial roles in virtually all aspects of biology and medicine. Their continual development contributes towards understanding and manipulating the normal action of enzymes and other proteins as well as in the development of new drugs.
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Synthetic biomimetic compounds play crucial roles in virtually all aspects of biology and medicine. Their continual development contributes towards understanding and manipulating the normal action of enzymes and other proteins as well as in the development of new drugs.
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Studies on Antibiotics and Enzyme Inhibitors
Clinical Infectious Diseases, 1987I have been studying antibiotics since 1944. In 1951, pathogenic bacteria resistant to antibiotic drugs had not yet appeared, and it seemed that effective chemotherapy for all bacterial diseases except tuberculosis was a fait accompli. Therefore, I initiated screening for antibiotics active against tumors.
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Angiotensin converting enzyme inhibitors
Pharmaceutisch Weekblad Scientific Edition, 1982Inhibition of angiotensin converting enzyme (ACE) in patients suffering from renovascular hypertension results in lowering of the blood-pressure. The development of captopril, an orally active ACE inhibitor and the structure-activity relationship of captopril analogues are described.
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Inhibitors of mitochondrial enzymes
Pharmacology & Therapeutics, 1979John B. Clark, John M. Land
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Enzyme inhibitors of microbial origin
Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1980The screening for enzyme inhibitors of microbial origin in the past decades has been a prosperous area to find new metabolites that are of potential importance as therapeutic or antibiotic agents. This review attempts a survey of recent achievements in this type of screening.
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Metal–Organic Framework-Based Enzyme Biocomposites
Chemical Reviews, 2021, Peter Wied, Francesco Carraro
exaly
1996
Mechanistic insight and structural information provide the starting points for two contrasting approaches to the design of enzyme inhibitors. Phosphorus-containing peptides are inhibitors of the zinc and aspartic peptidases that mimic key geometric and electronic characteristics of the transition states of these enzymes.
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Mechanistic insight and structural information provide the starting points for two contrasting approaches to the design of enzyme inhibitors. Phosphorus-containing peptides are inhibitors of the zinc and aspartic peptidases that mimic key geometric and electronic characteristics of the transition states of these enzymes.
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