Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel +6 more
wiley +1 more source
Safety evaluation of the food enzyme AMP deaminase from the genetically modified <i>Bacillus subtilis</i> strain CCTCC M 2023264. [PDF]
EFSA Panel on Food Enzymes (FEZ) +14 more
europepmc +1 more source
Clinical, Histologic, and Serological Predictors of Renal Function Loss in Lupus Nephritis
Objective Kidney survival is the ultimate goal in lupus nephritis (LN) management, but long‐term predictors remain inadequately studied, requiring long‐term follow‐up. This study aimed to identify baseline and early longitudinal predictors of kidney survival in the Accelerating Medicines Partnership LN longitudinal cohort.
Shangzhu Zhang +21 more
wiley +1 more source
Towards hybrid MOF@COF and COF@MOF platforms for next-generation biocatalysis. [PDF]
Chaparadza M +6 more
europepmc +1 more source
Formate Dehydrogenase: The Role of the AMP Cofactor Fragment in Stabilization of the Transition State for Enzyme-Catalyzed Hydride Transfer. [PDF]
Hegazy R, Koudelka AP, Richard JP.
europepmc +1 more source
Safety evaluation of the food enzyme glucan 1,4-α-maltohydrolase from the genetically modified <i>Bacillus licheniformis</i> strain DP-Dzb115. [PDF]
EFSA Panel on Food Enzymes (FEZ) +15 more
europepmc +1 more source
An Efficient and Stable PEG-Mediated Transformation System for Medicinal Fungus <i>Ophiocordyceps xuefengensis</i>: Optimization and Functional Validation. [PDF]
Feng X +6 more
europepmc +1 more source
Enhanced Proteomics Analysis with a Novel Recombinant Chymotrypsin Analogue Engineered for High Cleavage Specificity. [PDF]
Adoni KR +6 more
europepmc +1 more source
Synergistic effects of nitrogen, sewage sludge, and poultry manure on integrative fertilization for wheat and sugar beet in marginally saline soil. [PDF]
Veres S, Alshaal T, Elhawat N.
europepmc +1 more source

