Production Technology and Biocatalytic Properties of Proteolytic Enzyme Preparation
Тихонов Сергей Леонидович, заведующий кафедрой пищевой инженерии, д-р техн. наук, профессор, Уральский государственный экономический университет (г.
Тихонов, С.Л. +9 more
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Immobilization of Cow Rumen Fluid Cellulase by Entrapment in Calcium Alginate Beads [PDF]
Cellulases represent a class of enzyme which provide a key opportunity for achieving tremendous benefits of biomass utilization. Cellulase can be produced by fungi, bacteria or Actinomycetes.
Indah , Hartati +2 more
core
Substitution of antibodies and receptors with molecularly imprinted polymers in enzyme-linked and fluorescent assays [PDF]
A new technique for coating microtitre plates with molecularly imprinted polymers (MIP), specific for low-molecular weight analytes (epinephrine, atrazine) and proteins is presented.
Piletska, Elena V. +11 more
core +1 more source
USE OF BIOLOGICALLY ACTIVE SUBSTANCES OF THE HYDROLASE CLASS IN COMPOUND FEED FOR PIGS
The high efficiency of poultry and pigs is based on high-yielding breeds, balanced high-yielding mixed fodders and appropriate animal holding conditions. Recently, the tendency of increasing the efficiency of the nutritional potential of mixed fodder has
O. Y. KARUNSKYI, S. O. TSIKHOVSKYI
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Enzyme Producing Activity of Probiotics and Preparation of Compound Enzyme
Probiotics are a group of active microorganisms, which benefit the host by colonizing and changing the composition of host flora. It is of great significance to promote the development of human gastrointestinal nutrition and health by regulating the host
Xin Zhao +4 more
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source

