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Pancreatic enzyme replacement therapy in chronic pancreatitis
Best Practice & Research Clinical Gastroenterology, 2010Exocrine pancreatic insufficiency (EPI) is a serious condition which occurs in several diseases including chronic pancreatitis (CP), cystic fibrosis, pancreatic cancer, and as a result of pancreatic surgery. The lack or absence of pancreatic enzymes leads to an inadequate absorption of fat, proteins, and carbohydrates, causing steatorrhoea and ...
Djuna L. Cahen +3 more
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Enzyme replacement therapy in mucopolysaccharidosis type I
Acta Paediatrica, 2005AbstractMucopolysaccharidosis (MPS) type I is a lysosomal storage disorder caused by deficiency of the enzyme α‐l‐iduronidase (IDUA), which presents with a wide spectrum of phenotypes. Recently, enzyme replacement therapy (ERT) became available for patients with MPS I and has been demonstrated to be safe and effective in patients with the milder Hurler–
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2004
AbstractThis chapter traces the development of the field of enzyme replacement. It explores the major remaining problem — i.e., treatment of lysosomal storage diseases with a major neurologic component, because of insulation of the brain from the therapeutic enzyme by the blood-brain barrier.
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AbstractThis chapter traces the development of the field of enzyme replacement. It explores the major remaining problem — i.e., treatment of lysosomal storage diseases with a major neurologic component, because of insulation of the brain from the therapeutic enzyme by the blood-brain barrier.
openaire +1 more source
Renoprotection by enzyme replacement therapy
Current Opinion in Nephrology and Hypertension, 2004Jean-Pierre Grünfeld, Barry M. Brenner
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Radiation therapy‐associated toxicity: Etiology, management, and prevention
Ca-A Cancer Journal for Clinicians, 2021Kyle Wang
exaly
Enzyme replacement therapy for Fabry's disease
The Lancet, 2010David G. Warnock +3 more
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