Results 171 to 180 of about 108,982 (307)
Nuclear Factor I‐B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription
Advanced Science, EarlyView.This study identifies the transcription factor Nuclear Factor I‐B (NFIB) as a key suppressor of liver fibrosis. NFIB expression declines during hepatic stellate cell activation, and its overexpression reduces fibrosis in mice models. The mechanism involves NFIB directly repressing chemokine C─C motif ligand 5 (CCL5), thereby alleviating oxidative ...
Qianqian Chen +14 more
wiley +1 more source
Food Technology and Biotechnology, 2003 Lactose-intolerance is manifested in 50 % of the world’s population. This can be remediated by removing lactose from the diet or converting it into glucose and galactose with β-galactosidase (EC 3.2.1.23).
Samia Khan +2 more
doaj
Concomitant Repression by Gluten of HMP Shunt Dehydrogenases, Citrate Cleavage Enzyme and Malic Enzyme in Rat Liver and Adipose Tissue [PDF]
, 1976 G Livrea +3 more
openalex +1 more source
Advanced Science, EarlyView.In this study maize chloroplastic malate dehydrogenase7 (ZmMDH7), is identified as a Rhizoctonia solani resistance gene in maize. ZmMDH7 is regulated by transcription factor ZmWRKY44 via pathogens challenge to elevate mitochondrial ROS and SA signaling pathway.
Luyang Wei +9 more
wiley +1 more source
Regulation of the beta-1,3-glucanase system in Penicillium italicum: glucose repression of the various enzymes [PDF]
, 1978 T Santos +3 more
openalex +1 more source
REPRESSED AND INDUCED ENZYME FORMATION: A UNIFIED HYPOTHESIS [PDF]
Proceedings of the National Academy of Sciences, 1957 openaire +2 more sources
Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome
Advanced Science, EarlyView.Pharmacological SUMOylation inhibition (SUMOi) counteracts tumor immune evasion by unmasking an immunogenic HLA‐I peptide and neoepitope repertoire. By restoring HLA‐I ligand availability through increased antigen processing and presentation, enhanced proteasomal cleavage, and modulated TAP1 peptide affinity, SUMOi boosts tumor immunogenicity ...
Uta M. Demel +19 more
wiley +1 more source