The Role of the DNA Methyltransferase Family and the Therapeutic Potential of DNMT Inhibitors in Tumor Treatment. [PDF]
Kim DJ.
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ABSTRACT Komagataella phaffii, also known as Pichia pastoris, is a powerful host for recombinant protein production, in part due to its exceptionally strong and tightly controlled PAOX1 promoter. Most K. phaffii bioprocesses for recombinant protein production rely on PAOX1 to achieve dynamic control in two‐phase processes.
Shannon M. Hoffman+4 more
wiley +1 more source
Dual transcriptional inhibition of glutamate and alanine racemase is synergistic in Mycobacterium tuberculosis. [PDF]
McNeil MB, Cook GM, Krause KL.
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Nanomaterials for enhanced X‐ray‐triggered cancer therapy: Progress and prospects
This review summarizes the latest progress in nanomaterials for X‐ray‐triggered cancer therapy, highlighting their various advantages such as targeted delivery, reduced side effects, and enhanced therapeutic efficacy. Abstract X‐rays, a form of ionizing radiation with high energy and significant penetration capability, are commonly used in clinical ...
Yuanchun Chen+6 more
wiley +1 more source
Innovations, Challenges and Future Directions of T7RNA Polymerase in Microbial Cell Factories. [PDF]
Effendi SSW, Ng IS.
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The contribution of extracellular RNA and its derived biomaterials in disease management
The implications of exRNA's biological function and the structural uniqueness of RNA help establish a close connection between RNA, material, and modern medicine. Abstract The RNA found in the circular system is known as extracellular RNA (exRNA). This kind of RNA has been found to play a biological role similar to that of a messenger. They can be used
Yu Wei+8 more
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Regulation of nucleus-encoded trans-acting factors allows orthogonal fine-tuning of multiple transgenes in the chloroplast of Chlamydomonas reinhardtii. [PDF]
Mordaka PM+7 more
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Deciphering the skeletal interoceptive circuitry to control bone homeostasis
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu+7 more
wiley +1 more source
Effect of Phosphate Starvation on Gene Expression in Komagataella phaffii Cells. [PDF]
Ishtuganova VV+4 more
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