Results 51 to 60 of about 2,217,916 (339)
bioRxiv, 2019 Pumilio is an RNA-binding protein that represses a network of mRNAs to control embryogenesis, stem cell fate, fertility, and neurological functions in Drosophila.
René M. Arvola +6 more
semanticscholar +1 more source
Effective description of bistability and irreversibility in apoptosis [PDF]
arXiv, 2021 Apoptosis is a mechanism of programmed cell death in which cells engage in a controlled demolition and prepare to be digested without damaging their environment. In normal conditions apoptosis is repressed, until it is irreversibly induced by an appropriate signal.
arxiv
Journal of Biological Chemistry, 2017 Inflammatory signals induce feedback and feedforward systems that provide temporal control. Although glucocorticoids can repress inflammatory gene expression, glucocorticoid receptor recruitment increases expression of negative feedback and feedforward ...
R. Newton +3 more
semanticscholar +1 more source
Transcriptional Repression of Catalase in Mouse Skin Tumor Progression
Neoplasia: An International Journal for Oncology Research, 2004 Previous studies in our laboratory have shown that the elevation of reactive oxygen species levels and the repression of the antioxidant enzyme, catalase, played a critical role in the in vitro progression of benign papilloma cells to malignant carcinoma
Kevin A. Kwei +3 more
doaj +1 more source
The UBC9 E2 SUMO conjugating enzyme binds the PR-Set7 histone methyltransferase to facilitate target gene repression. [PDF]
PLoS ONE, 2011 PR-Set7/Set8/KMT5a is a chromatin-modifying enzyme that specifically monomethylates lysine 20 of histone H4 (H4K20me1). In this study we attempted to identify PR-Set7-interacting proteins reasoning that these proteins would provide important insights ...
Tanya M Spektor +3 more
doaj +1 more source
Differential Evolution of α-Glucan Water Dikinase (GWD) in Plants
Plants, 2020 The alpha-glucan water dikinase (GWD) enzyme catalyzes starch phosphorylation, an integral step in transitory starch degradation. The high phosphate content in stored starch has great industrial value, due to its physio–chemical properties making it more
Muyiwa S. Adegbaju +4 more
doaj +1 more source
ASH1-catalyzed H3K36 methylation drives gene repression and marks H3K27me2/3-competent chromatin
eLife, 2018 Methylation of histone H3 at lysine 36 (H3K36me), a widely-distributed chromatin mark, largely results from association of the lysine methyltransferase (KMT) SET-2 with RNA polymerase II (RNAPII), but most eukaryotes also have additional H3K36me KMTs ...
Vincent T Bicocca +4 more
doaj +1 more source
The molecular mechanism for carbon catabolite repression of the chitin response in Vibrio cholerae.
PLoS Genetics, 2023 Vibrio cholerae is a facultative pathogen that primarily occupies marine environments. In this niche, V. cholerae commonly interacts with the chitinous shells of crustacean zooplankton. As a chitinolytic microbe, V.
Virginia E Green +3 more
doaj +1 more source
Lipids in Health and Disease, 2011 Citrus flavonoids have been shown to decrease plasma lipid levels, improve glucose tolerance, and attenuate obesity. One possible mechanism underlying these physiological effects is reduction of hepatic levels of the mRNA for stearoyl-CoA desaturase-1 ...
Shukla Shivendra D +4 more
doaj +1 more source
Negative Feedback and Physical Limits of Genes [PDF]
Journal of Theoretical Biology 248:1 (2011) 82-91, 2014 This paper compares the auto-repressed gene to a simple one (a gene without auto-regulation) in terms of response time and output noise under the assumption of fixed metabolic cost. The analysis shows that, in the case of non-vanishing leak expression rate, the negative feedback reduces both the switching on and switching off times of a gene. The noise
arxiv +1 more source