Results 151 to 160 of about 559,990 (314)

The crystal structure of Pyrococcus furiosus ornithine carbamoyltransferase reveals a key role for oligomerization in enzyme stability at extremely high temperatures

, 1998
Vincent Villeret, Bernard Clantin, Catherine Tricot, Christianne Legrain, Martine Roovers, Victor Stalon, Nicolas Glansdorff, Jozef Van Beeumen   +7 more
openalex   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Large scale production and crystallization of acid carboxypeptidase from submerged culture of Penicillium janthinellum, and stability of the crystalline enzyme.

, 1975
Sadaji Yokoyama, Akira Oobayashi, Osamu Tanabe, Eiji Ichishima   +3 more
openalex   +2 more sources

A green approach to the synthesis of novel “Desert rose stone”-like nanobiocatalytic system with excellent enzyme activity and stability [PDF]

, 2014
Min Wang, Wenjing Bao, Jiong Wang, Kang Wang, Jing‐Juan Xu, Hong‐Yuan Chen, Xing‐Hua Xia   +6 more
openalex   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Engineering Glutathione Peroxidase-Loaded Polymeric Nanogels Through a Grafting-To Route for Enhanced Enzyme Stability and Activity. [PDF]

Polymers (Basel)
Basak S.
europepmc   +1 more source

Pro-opiomelanocortin and its Processing Enzymes Associate with Plaque Stability in Human Atherosclerosis – Tampere Vascular Study [PDF]

, 2018
Petteri Rinne, Leo‐Pekka Lyytikäinen, Emma Raitoharju, James J. Kadiri, Ivana Kholová, Mika Kähönen, Terho Lehtimäki, Niku Oksala   +7 more
openalex   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Enhanced enzyme stability at the interphase of water-oil for continuous-flow olefin epoxidation. [PDF]

Nat Commun
Zhang M, Wang M, Mi Y, Li T, Hou D, Li H, Tong X, Zhang T, Yi H, Yang H.   +9 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source