Results 171 to 180 of about 559,990 (314)

Enzyme Immobilization on Metal Organic Frameworks: the Effect of Buffer on the Stability of the Support

, 2022
Kim Shortall, Fernando Otero, Simon Bendl, Tewfik Soulimane, Edmond Magner   +4 more
openalex   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Immobilization of Thiol-Modified Horseradish Peroxidase on Gold Nanoparticles Enhances Enzyme Stability and Prevents Proteolytic Digestion. [PDF]

Langmuir
Breausche FE, Somerlot A, Walder J, Osei K, Okyem S, Driskell JD.   +5 more
europepmc   +1 more source

Increasing Enzyme Stability and Activity through Hydrogen Bond-Enhanced Halogen Bonds. [PDF]

Biochemistry, 2018
Carlsson AC, Scholfield MR, Rowe RK, Ford MC, Alexander AT, Mehl RA, Ho PS.   +6 more
europepmc   +1 more source

Review for "Structural basis of mutants of <scp>PET</scp> ‐degrading enzyme from <i>Saccharomonospora viridis</i> <scp>AHK190</scp> with high activity and thermal stability"

, 2020

openalex   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Solvent concentration at 50% protein unfolding may reform enzyme stability ranking and process window identification. [PDF]

Nat Commun
Sorgenfrei FA, Sloan JJ, Weissensteiner F, Zechner M, Mehner NA, Ellinghaus TL, Schachtschabel D, Seemayer S, Kroutil W.   +8 more
europepmc   +1 more source

Glucose-6-phosphate dehydrogenase enzyme stability in filter paper dried blood spots. [PDF]

Clin Biochem, 2017
Flores SR, Hall EM, De Jesús VR.
europepmc   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Horseradish Peroxidase Immobilized onto Mesoporous Magnetic Hybrid Nanoflowers for Enzymatic Decolorization of Textile Dyes: A Highly Robust Bioreactor and Boosted Enzyme Stability. [PDF]

ACS Omega
Bakar B, Akbulut M, Ulusal F, Ulu A, Özdemir N, Ateş B.   +5 more
europepmc   +1 more source