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Applications and limitations of AI tools in enzyme design. [PDF]

open access: yesProtein Sci
Teijeiro-Juiz R   +6 more
europepmc   +1 more source
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The enzyme stability of dehydropeptides

Biochemical and Biophysical Research Communications, 1978
Abstract A pentapeptide, Z-Gly-Gly-Phe-Phe-Ala · OH (1b) and the corresponding unsaturated pentapeptide, Z-Gly-Gly-Phe-Δ Z Phe-Ala · OH (1a) , have been synthesized. The saturated compound (1b) was rapidly hydrolyzed by both chymotrypsin and thermolysin to the expected products, but the dehydropeptide was completely unhydrolyzed by ...
M L, English, C H, Stammer
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