Results 71 to 80 of about 784,273 (205)

Pegademase bovine (PEG-ADA) for the treatment of infants and children with severe combined immunodeficiency (SCID)

, 2009
Adenosine deaminase deficiency (ADA) is a rare, inherited disorder of purine metabolism characterized by immunodeficiency, failure to thrive and metabolic abnormalities. A lack of the enzyme ADA allows accumulation of toxic metabolites causing defects of
Claire Booth, Booth, C, H Bobby Gaspar, Gaspar, HB   +3 more
core  

Study of enzyme replacement therapy for Gaucher Disease: comparative analysis of clinical and laboratory parameters at diagnosis and after two, five and ten years of treatment

Revista Brasileira de Hematologia e Hemoterapia, 2014
Objective: To evaluate the impact of enzyme replacement therapy for Gaucher Disease on clinical and laboratory parameters after two, five and ten years of treatment. Methods: Data were collected from patient records and analyzed using BioEstat software
Ana Maria Almeida Souza, Thiago Pimentel Muniz, Rafael Maciel Brito   +2 more
doaj   +1 more source

Oral Enzyme Therapy in Systemic Analgetic Treatment

, 2022
The possibility of an oral enzyme combination being able to replace diclofenac in the treatment of pain and inflammation is discussed. Oral enzyme therapy involves the use of proteolytic enzymes like bromelain, serratiopeptidase, trypsin, rutin, and ...
Mutzberg, Lisa-Camilla
core  

Preclinical evaluation of a prostate-targeted gene-directed enzyme prodrug therapy delivered by ovine atadenovirus

, 2004
Gene-directed enzyme prodrug therapy (GDEPT) based on the Escherichia coli enzyme, purine nucleoside phosphorylase (PNP), provides a novel strategy for treating slowly growing tumors like prostate cancer (CaP).
Cameron, F, Martiniello-Wilks, R, Smith, IK, N Coulston, XY Wang, PJ Russell, Shaw, JM, LK Webster, T Ho, Molloy, PL, Russel, PJ, Cooke-Yarborough, C, GW Both, Both, GW, Webster, LK, PL Molloy, IK Smith, R Martiniello-Wilks, Wang, XY, Moghaddam, M, Ho, T, Coulston, N, F Cameron, Lockett, TJ, JM Shaw, M Moghaddam, C Cooke-Yarborough, TJ Lockett   +27 more
core   +1 more source

Enzyme therapy: a forerunner in catalyzing a healthy society?

, 2020
The use of enzymes in various industries has been prevalent for centuries. However, their potency as therapeutics remained latent until the late 1950 s, when scientists finally realized the gold mine they were sitting on.
Datta, Saptashwa, Zayed, Hatem, George Priya Doss, C, Selvarajan, E, Rajnish, K Narayanan, Melvin Samuel, S   +5 more
core   +1 more source

Enzyme replacement therapy compared with best supportive care for the treatment of Pompe Disease: a systematic review and network meta-analysis

Health Technology Assessment
Background Late-onset Pompe disease is a rare inherited genetic condition that causes progressive muscle dysfunction and damage. As the disease advances, the progressive weakening of respiratory muscles significantly increases the risk of respiratory ...
Mark Corbett, Chinyereugo Umemneku-Chikere, Sarah Nevitt, Nyanar Jasmine Deng, Matthew Walton, Helen Fulbright, Chong Yew Tan, Robin Lachmann, Rachel Churchill, Robert Hodgson   +9 more
doaj   +1 more source

Immobilized nanoparticles-mediated enzyme therapy; promising way into clinical development. [PDF]

Discov Nano, 2023
Zangi AR, Amiri A, Borzouee F, Bagherifar R, Pazooki P, Hamishehkar H, Javadzadeh Y.   +6 more
europepmc   +1 more source

Early Video-assisted Thoracoscopic Surgery or Intrapleural Enzyme Therapy in Pleural Infection: A Feasibility Randomized Controlled Trial. The Third Multicenter Intrapleural Sepsis Trial-MIST-3. [PDF]

Am J Respir Crit Care Med, 2023
Bedawi EO, Stavroulias D, Hedley E, Blyth KG, Kirk A, De Fonseka D, Edwards JG, Internullo E, Corcoran JP, Marchbank A, Panchal R, Caruana E, Kadwani O, Okiror L, Saba T, Purohit M, Mercer RM, Taberham R, Kanellakis N, Condliffe AM, Lewis LG, Addala DN, Asciak R, Banka R, George V, Hassan M, McCracken D, Sundaralingam A, Wrightson JM, Dobson M, West A, Barnes G, Harvey J, Slade M, Chester-Jones M, Dutton S, Miller RF, Maskell NA, Belcher E, Rahman NM.   +39 more
europepmc   +1 more source

Enzyme Therapy: Current Challenges and Future Perspectives. [PDF]

Int J Mol Sci, 2021
de la Fuente M, Lombardero L, Gómez-González A, Solari C, Angulo-Barturen I, Acera A, Vecino E, Astigarraga E, Barreda-Gómez G.   +8 more
europepmc   +1 more source

Impact of enzyme replacement therapy and hematopoietic stem cell transplantation in patients with Morquio A syndrome

, 2015
Shunji Tomatsu,1,2 Kazuki Sawamoto,1 Carlos J Alméciga-Díaz,3 Tsutomu Shimada,1 Michael B Bober,1 Yasutsugu Chinen,4 Hiromasa Yabe,5 Adriana M Montaño,6 Roberto Giugliani,7 Francyne Kubaski,1,8 Eriko ...
Montaño AM, Rodríguez-López A, Alméciga-Díaz CJ, Sánchez OF, Mason RW, Tomatsu S, Shimada T, Kubaski F, Bober MB, Chinen Y, Yasuda E, Espejo-Mojica AJ, Orii T, Barrera LA, Yabe H, Sawamoto K, Giugliani R, Mackenzie WG   +17 more
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