Results 1 to 10 of about 4,643,656 (420)
Accelerated search kinetics mediated by redox reactions of DNA repair enzymes [PDF]
Biophysical Journal, volume 96, pp 3949-3958, (2009), 2009 A Charge Transport (CT) mechanism has been proposed in several papers (e.g., Yavin, et al. PNAS, v102 3546 (2005)) to explain the localization of Base Excision Repair (BER) enzymes to lesions on DNA. The CT mechanism relies on redox reactions of iron-sulfur cofactors that modify the enzyme's binding affinity.
Bai +32 more
arxiv +5 more sources
Identification of functionally related enzymes by learning-to-rank methods [PDF]
arXiv, 2014 Enzyme sequences and structures are routinely used in the biological sciences as queries to search for functionally related enzymes in online databases. To this end, one usually departs from some notion of similarity, comparing two enzymes by looking for correspondences in their sequences, structures or surfaces. For a given query, the search operation
Airola, Antti +8 more
arxiv +3 more sources
Absolute diffusion measurements of active enzyme solutions by NMR [PDF]
, 2018 The diffusion of enzymes is of fundamental importance for many biochemical processes. Enhanced or directed enzyme diffusion can alter the accessibility of substrates and the organization of enzymes within cells. Several studies based on fluorescence correlation spectroscopy (FCS) report enhanced diffusion of enzymes upon interaction with their ...
Fischer, Peer +2 more
arxiv +3 more sources
Enzyme localization can drastically affect signal amplification in signal transduction pathways [PDF]
, 2007 Push-pull networks are ubiquitous in signal transduction pathways in both prokaryotic and eukaryotic cells. They allow cells to strongly amplify signals via the mechanism of zero-order ultrasensitivity. In a push-pull network, two antagonistic enzymes control the activity of a protein by covalent modification.
van Albada, Siebe B. +1 more
arxiv +6 more sources
Regulation of antioxidant enzymes: a significant role for melatonin
Journal of Pineal Research, 2004 : Antioxidant enzymes form the first line of defense against free radicals in organisms. Their regulation depends mainly on the oxidant status of the cell, given that oxidants are their principal modulators.
Carmen Rodríguez +2 more
exaly +2 more sources
Regulating Retinoic Acid Availability during Development and Regeneration: The Role of the CYP26 Enzymes. [PDF]
, 2020 This review focuses on the role of the Cytochrome p450 subfamily 26 (CYP26) retinoic acid (RA) degrading enzymes during development and regeneration. Cyp26 enzymes, along with retinoic acid synthesising enzymes, are absolutely required for RA homeostasis
Roberts, C
core +4 more sources
Frontiers in Microbiology, 2021 Spore-based probiotics offer important advantages over other probiotics as they can survive the harsh gastric conditions of the stomach and bile salts in the small intestine, ultimately germinating in the digestive tract.
Joan Colom +6 more
doaj +1 more source
Nature Communications, 2022 Haloacid dehalogenase-like phosphatases are widespread across all domains of life and play a crucial role in the regulation of levels of sugar phosphate metabolites in cells.
Chaoyu Tian +8 more
doaj +1 more source
Screening, identification, and degradation characteristics of 3-methylindole degrading bacteria
Frontiers in Environmental Science, 2022 3-Methylindole is a major component of organic pollutants in livestock compost, which can contribute to the deterioration of the environment in livestock farms and their surrounding areas.
Hong Hu +8 more
doaj +1 more source
Foods, 2021 The scope of this investigation aimed at obtaining and stabilizing bioactive products derived from Lycium barbarum seeds and peels, which were the byproducts in the processing of fruit juice.
Yan Men +4 more
doaj +1 more source