Results 101 to 110 of about 159,463 (305)

A novel mechanism of RNase L inhibition: Theiler\u27s virus L* protein prevents 2-5A from binding to RNase L [PDF]

, 2018
The OAS/RNase L pathway is one of the best-characterized effector pathways of the IFN antiviral response. It inhibits the replication of many viruses and ultimately promotes apoptosis of infected cells, contributing to the control of virus spread ...
Drappier, Melissa, Elliot, Ruth, Jha, Babal Kant, Michiels, Thomas, Silverman, Robert H, Stone, Sasha, Vertommen, Didier, Weiss, Susan R, Zhang, Rong   +8 more
core   +4 more sources

Coagulative Granular Hydrogels with an Enzyme Catalyzed Fibrin Network for Endogenous Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Coagulative granular hydrogels are composed of packed thrombin‐functionalized microgels that catalyze the conversion of fibrinogen into a secondary fibrin network, filling the interstitial voids. This bio‐inspired approach stabilizes the biomaterial to match the robustness of bulk hydrogels without compromising injectability, mimicking the initial ...
Zhipeng Deng, Camila B. Tovani, Simona Bianco, Gianni Comandini, Aya Elghajiji, Mina Aleemardani, Roxana Moscalu, Jeremie Zappia, Bianca Fernandes, Olivia Annett, Chrissy L. Hammond, Jason Wong, Dave J. Adams, Fabrizio Scarpa, Michael R. Whitehouse, Annela M. Seddon, James P. K. Armstrong   +16 more
wiley   +1 more source

Properties and stabilization of an extracellular α-glucosidase from the extremely thermophilic archaebacteria Thermococcus strain AN 1: enzyme activity at 130°C [PDF]

, 1996
An extracellular α-glucosidase from the thermophilic archaebacterium Thermococcus strain AN1 was purified 875-fold in five steps (Hiload Q-Sepharose, phenyl Sepharose, HPHT-hydroxyapatite, gel filtration and Mono Q chromatography) with a yield of 4%.
Daniel, Roy M., Petach, Helen H., Piller, Karin   +2 more
core   +2 more sources

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Immobilized phosphorylase for synthesis of polysaccharides from glucose [PDF]

, 1972
Continuous processes for enzymatic production of carbohydrates from glucose are discussed. Key reactant in process is identified as phosphorylase which catalyzes reversible formation or degradation of polysaccharide.
Marshall, D. L.
core   +1 more source

Inhibition-based first-generation electrochemical biosensors: theoretical aspects and application to 2,4-dichlorophenoxy acetic acid detection [PDF]

, 2016
In this work, several theoretical aspects involved in the first-generation inhibition-based electrochemical biosensor measurements have been discussed. In particular, we have developed a theoretical-methodological approach for the characterization of the
Antiochia, Riccarda, Bollella, Paolo, Favero, Gabriele, Fusco, Giovanni, Mazzei, Franco, Sanzo', Gabriella, Tortolini, Cristina   +6 more
core   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Techniques for immobilizing enzymes to create durable and effective biocatalysts

Results in Chemistry
This comprehensive review focuses on strategies for creating efficient and robust immobilized biocatalysts. It explores various physicochemical approaches that hold promise for enzyme stabilization and enhancement of catalytic potential.
Seyed Mehrdad Mirsalami, Mahsa Mirsalami, Amin Ghodousian   +2 more
doaj   +1 more source

Enhancement of biodegradation potential of catechol 1,2-dioxygenase through its immobilization in calcium alginate gel

Electronic Journal of Biotechnology, 2014
Background: In biodegradation processes free enzymes often undergo deactivation. Thus, it is very important to obtain highly stable enzymes by different methods.
Urszula Guzik, Katarzyna Hupert-Kocurek, Ariel Marchlewicz, Danuta Wojcieszyńska   +3 more
doaj   +1 more source

A novel hydrogen peroxide biosensor based on modified electrode with hemoglobin and zinc oxide nanoparticles [PDF]

, 2012
In this study, direct electron transfer between immobilized hemoglobin (Hb) and zinc oxide nanoparticles modified carbon paste electrode was studied. Direct electrochemical response of Hb on the modified electrode can be achieved and a couple of well ...
Arabnezhad-Khanooki, T., Farasat, A., Mazdapour, M., Mirzaeinasab, F., Negahdary, M., Noughabi, M.T., Rezaei, E., Yousefi-Telori, B.   +7 more
core