Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Life on the rocks: unexpected enzyme activity of the extremophilic black fungus <i>Knufia chersonesos</i>. [PDF]
Mihalyi S +6 more
europepmc +1 more source
Thermal Effects on Bioaccumulation and Antioxidant Enzyme Response in the Liver and Gills of Tilapia Oreochromis niloticus Exposed to Arsenic [PDF]
EunYoung Min +2 more
openalex +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Origin and Evolution of Key Enzymes in the Anammox Pathway Revisited. [PDF]
Hägglund E +5 more
europepmc +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Diversity of FAAL enzymes and prediction of their substrate specificity using FAALPred. [PDF]
Liong A, Pereira LM, Leão PN.
europepmc +1 more source
Substrate mass transfer: analytical approach for immobilized enzyme reactions
R. Senthamarai, T. N. Saibavani
openalex +1 more source

