Results 181 to 190 of about 2,028,343 (313)

Covalent Immobilisation of Different Enzymes on Hydroxyapatite, an Alternative Green Support

open access: yes
The implementation of biocatalysis in industrial processes has been hampered by poor long-term stability and difficult recyclability of enzymes. A viable solution to solve these problems is the immobilisation of the biocatalyst on insoluble supports ...
Leonardo Gelati   +3 more
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Remodeling of tRNA modification in Trypanosoma cruzi life forms. [PDF]

open access: yesPLoS Pathog
Silva HGS   +7 more
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Reaction Optimization for Enzymatic Deconstruction of Industrially Relevant Nylon Composites. [PDF]

open access: yesChembiochem
Bourgery C   +10 more
europepmc   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

open access: yesFEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey   +4 more
wiley   +1 more source

Mechanisms of actin-binding proteins in glycolysis-cytoskeleton coupling. [PDF]

open access: yesJ Transl Med
Zhang Z   +9 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy