Results 191 to 200 of about 3,264,500 (360)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Novel GH115 xylan α-1,2-glucuronidases with distinct preferences for xylan-derived oligomers and polymers. [PDF]

Protein Sci
Leontakianakou S, Le SB, Sundin A, Jasilionis A, Nguyen GS, Nordborg A, Gottumukkala LD, Grey C, Lewin AS, Karlsson EN.   +9 more
europepmc   +1 more source

Extracellular matrix associated proteins and processing enzymes as urinary biomarkers of Chronic Kidney Disease [PDF]

, 2015
Michelle Da Silva Lodge
openalex  

Elevated Liver Enzymes in Patients with COVID-19: Look, but Not Too Hard [PDF]

, 2020
Andrew M. Moon, A. Sidney Barritt
openalex   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

How enzymes make the right choice during biosynthesis. [PDF]

Elife
Ramírez AS, Perez C.
europepmc   +1 more source

Enzymes and Enzyme Mimics

, 2010
Woggon, W. -D., Chougnet, Antoinette
openaire   +3 more sources

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Gap Analysis of Metabolic Conversions of Off-Flavors and Antinutrients in Plant-Based Substrates. [PDF]

Compr Rev Food Sci Food Saf
Kuijpers RI, de Moya Clark IO, Cavaco T, Nemanič V, Tagliabue B, Valero-Abad A, Wennekers WM, Zhang M, Van Zwet K, Abeln S, Moco S, Paul CE, Mouhib H, Notebaart RA, Smid EJ, Teusink B, Bachmann H.   +16 more
europepmc   +1 more source

Faculty Opinions recommendation of Maternal undernutrition programs offspring adrenal expression of steroidogenic enzymes.

, 2011
Holly LaVoie, Steven R. King
openalex   +2 more sources