Results 111 to 120 of about 24,045 (247)

Cadherin‐26 Facilitates Transepithelial Migration of Eosinophils in Eosinophilic Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Eosinophilic chronic rhinosinusitis with nasal polyps (eCRSwNP) is characterized by persistent sinonasal inflammation and marked eosinophilic infiltration. Although the relationship between eosinophils and NP formation has been extensively studied, the mechanisms governing eosinophil transepithelial migration into the nasal mucosa ...
Yeong‐In Jo, Jee Won Moon, Joo‐Hoo Park, Hwa Eun Yang, Subin Cho, Hyeongguk Son, Hyun‐Woo Yang, Il‐Ho Park   +7 more
wiley   +1 more source

Machine Learning‐Enhanced Clinical Decision Support for Diagnosing Sinusitis With Nasal Endoscopy

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Sinusitis is a prevalent disease for which nasal endoscopy (NE) is an optimal diagnostic modality. However, NE accuracy is limited by inter‐operator variability in landmark identification and localization of mucus that is necessary for sinusitis diagnosis. We sought to develop a novel multi‐class machine learning (ML) framework that
Dipesh Gyawali, Thomas Mundy, Majid Hosseini, Morteza Bodaghi, Akio Fujiwara, Sejal Shyam Bhatia, Kayla Baker, Elena Bartolone, Dhara Patel, Henry Chu, Raju Gottumukkala, Jonathan Bidwell, Edward D. McCoul   +12 more
wiley   +1 more source

Clinical Implications of Low Absolute Blood Eosinophil Count in the SPIROMICS COPD Cohort [PDF]

, 2021
William LeMaster, P. Miguel Quibrera, David Couper, Donald P. Tashkin, Eugene R. Bleecker, Claire M. Doerschuk, Victor E. Ortega, C.B. Cooper, MeiLan K. Han, Prescott G. Woodruff, Wanda K. O’Neal, Wayne H. Anderson, Neil E. Alexis, Jeffrey L. Curtis, Russell P. Bowler, R. Graham Barr, Robert J. Kaner, Mark T. Dransfield, Robert Paine, V. Kim, Fernando J. Martínez, Annette T. Hastie, Igor Barjaktarević   +22 more
openalex   +1 more source

The Global Airways in Practice: Long‐term Effects of Mepolizumab With or Without FESS on Type 2 Inflammation in Patients With CRSwNP

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a type 2 inflammatory disease often associated with asthma. The global airway hypothesis suggests bidirectional inflammatory interactions between upper and lower airways. Mepolizumab, an anti–IL‐5 therapy, treats conditions systemically, while functional endoscopic sinus surgery ...
Jens Tidemandsen, Vibeke Backer, Anne Sophie Homøe, Thomas H. L. Jensen, Kasper Aanæs, Howraman Meteran, Morten Hostrup, Lukas Moesgaard, Christiane Haase, Peter G. Gibson   +9 more
wiley   +1 more source

Development of Artificial Intelligence for Quantitative Assessment of Nasal Inflammatory Cytology in Chronic Rhinitis by Whole‐Slide Images

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinitis (CR) is currently recognized as a syndrome that manifests in different phenotypes. We aimed to establish an artificial intelligence system (quantitative assessment of nasal inflammatory cytology, QANIC) on the basis of whole‐slide images (WSIs) to enable quantitative assessment of nasal inflammatory cells.
Xu Zhang, Xu Xu, Weiwei Liu, Long Qin, Yu Song, Jingyun Li, Lin Xi, Chengshuo Wang, Luo Zhang, Yuan Zhang   +9 more
wiley   +1 more source

NOD2 and TLR2 ligands trigger the activation of basophils and eosinophils by interacting with dermal fibroblasts in atopic dermatitis-like skin inflammation [PDF]

, 2015
Delong Jiao, Chun Kwok Wong, Huaina Qiu, Jie Dong, Zhe Cai, Man Chu, Kam‐Lun Ellis Hon, Miranda Sin‐Man Tsang, Christopher Wai-Kei Lam   +8 more
openalex   +1 more source

Eosinophil Peroxidase as a Dynamic Indicator of Treatment Response in Eosinophilic Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Eosinophil peroxidase (EPX) in nasal mucus correlates with markers of type 2 inflammation and tissue eosinophilia in chronic rhinosinusitis (CRS). This study evaluated EPX as a dynamic biomarker across treatment modalities and its potential prognostic value in eosinophilic CRS.
Jacquelyn K. Callander, Annabelle R. Charbit, Camryn Marshall, Kritika Khanna, Steven D. Pletcher, Jose G. Gurrola II, Andrew H. Murr, Monica Tang, Andrew N. Goldberg, Patricia A. Loftus   +9 more
wiley   +1 more source

Eosinophils in eosinophilic endomyocardial disease [PDF]

Postgraduate Medical Journal, 1986
openaire   +2 more sources

Optimizing the dengue virus infection mouse model: Comparing different backgrounds and infection route for enhanced stability

Animal Models and Experimental Medicine, EarlyView.
Optimized dengue fever animal model: IFNAR−/− BALB/c mice with intraperitoneal injection. Background screening: Between IFNAR−/− (BALB/c, C57BL/6) and AG129 mice, IFNAR−/−BALB/c exhibited the most severe symptoms: (1) highest weight loss and clinical scores; (2) peak viremia (5.44 log10 RNA copies/mL, day 4); (3) significant organ damage (liver/brain ...
Dan Liao, Ming Zhong, Wenjiang Zheng, Zhendong Guo, Ye Zhou, Qiuhong Li, Lijuan Qiu, Liangwen Yu, Haishan Long, Geng Li   +9 more
wiley   +1 more source

Cutting Edge: Serotonin Is a Chemotactic Factor for Eosinophils and Functions Additively with Eotaxin [PDF]

, 2004
Stefen A. Boehme, Francisco M. Lio, Lyudmila Sikora, Terlika S. Pandit, Karine Lavrador, P. Sriramarao, P. Sriramarao   +6 more
openalex   +1 more source