Results 121 to 130 of about 186,812 (342)
Acute Exercise Challenge and Airway Dynamics in Youth With Sickle Cell Anemia: A Multicenter Study
Changes in airway dynamics in children with sickle cell anemia after maximal cardiopulmonary exercise testing and a controlled intensity interval excercise challenge. ABSTRACT Sickle cell anemia (SCA) leads to reduced physical functioning and cardiopulmonary fitness. Prior studies suggest that airway hyperresponsiveness to bronchoprovocation testing is
Robyn T. Cohen +9 more
wiley +1 more source
Nasal polyposis: eosinophils and interleukin‐5 [PDF]
Matthias Krämer, Gerd Rasp
openalex +1 more source
ABSTRACT Background Eosinophilic chronic rhinosinusitis with nasal polyps (eCRSwNP) is characterized by persistent sinonasal inflammation and marked eosinophilic infiltration. Although the relationship between eosinophils and NP formation has been extensively studied, the mechanisms governing eosinophil transepithelial migration into the nasal mucosa ...
Yeong‐In Jo +7 more
wiley +1 more source
Machine Learning‐Enhanced Clinical Decision Support for Diagnosing Sinusitis With Nasal Endoscopy
ABSTRACT Background Sinusitis is a prevalent disease for which nasal endoscopy (NE) is an optimal diagnostic modality. However, NE accuracy is limited by inter‐operator variability in landmark identification and localization of mucus that is necessary for sinusitis diagnosis. We sought to develop a novel multi‐class machine learning (ML) framework that
Dipesh Gyawali +12 more
wiley +1 more source
Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils. [PDF]
Paul Ponath +8 more
openalex +1 more source
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a type 2 inflammatory disease often associated with asthma. The global airway hypothesis suggests bidirectional inflammatory interactions between upper and lower airways. Mepolizumab, an anti–IL‐5 therapy, treats conditions systemically, while functional endoscopic sinus surgery ...
Jens Tidemandsen +9 more
wiley +1 more source
Nanoparticle‐based tolerogenic vaccines harness controlled antigen delivery and immunomodulation to establish tolerance in autoimmunity and allergy. This review outlines how nanoparticle design (size, shape, composition, administration route) influences biodistribution and immune‐cell targeting.
Benjamin E. Nachod +3 more
wiley +2 more sources
ABSTRACT Background Chronic rhinitis (CR) is currently recognized as a syndrome that manifests in different phenotypes. We aimed to establish an artificial intelligence system (quantitative assessment of nasal inflammatory cytology, QANIC) on the basis of whole‐slide images (WSIs) to enable quantitative assessment of nasal inflammatory cells.
Xu Zhang +9 more
wiley +1 more source
Eosinophil Cationic Protein (ECP), a predictive marker of bullous pemphigoid severity and outcome [PDF]
Delphine Giusti +6 more
openalex +1 more source

