Results 111 to 120 of about 110,785 (312)

Unveiling the Intricacies of Autophagy in Asthma: Unraveling Novel Therapeutic Avenues

Frontiers in Bioscience-Landmark
Understanding the pathogenesis of different phenotypes of asthma, including glucocorticoid-dependent and glucocorticoid-resistant asthma, is crucial for the development of effective treatments.
Junjun Peng, Na Lu, Shucheng Hua, Lei Song, Han Liu   +4 more
doaj   +1 more source

Eosinophil: A New Circulating Biomarker for Risk of Poor Outcome in Stroke Patients Undergoing Mechanical Thrombectomy

Clinical Interventions in Aging, 2023
Shuai Yu,* Zhi-Chao Huang,* Huai-Shun Wang,* Shan-Wen Liu, Shou-Jiang You, Jie Hou, Zhi-Liang Guo, Guo-Dong Xiao Department of Neurology and Suzhou Clinical Research Center of Neurological Disease, The Second Affiliated Hospital of Soochow ...
Yu S, Huang ZC, Wang HS, Liu SW, You SJ, Hou J, Guo ZL, Xiao GD   +7 more
doaj  

Eosinophil Recruitment and Activation: The Role of Lipid Mediators

Frontiers in Pharmacology, 2013
Eosinophils are effector cells that migrate toward several mediators released at inflammatory sites to perform their multiple functions. The mechanisms driving eosinophil selective accumulation in sites of allergic inflammation are well established and ...
Tatiana eLuna-Gomes, Patricia eBozza, Christianne eBandeira-Melo   +2 more
doaj   +1 more source

Eosinophil counts in first COPD hospitalizations: a comparison of health service utilization [PDF]

, 2018
Maryse Bélanger,1,2 Simon Couillard,1,2 Josiane Courteau,1 Pierre Larivée,1,2 Thomas G Poder,1,3,4 Nathalie Carrier,1 Kim Girard,1 Felix-Antoine Vézina,1,2 Alain Vanasse1,4 1Research Center, Centre hospitalier universitaire de ...
Vanasse A, Larivée P, Carrier N, Poder TG, Girard K, Vézina FA, Couillard S, Courteau J, Bélanger M   +8 more
core  

Allergic Rhinitis Amplifies Asthma Risk in Patients With Chronic Rhinosinusitis: A Large‐Scale Retrospective Cohort Analysis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) and allergic rhinitis (AR) are two highly prevalent airway diseases in the United States. While the coexistence of CRS and asthma is well recognized, less is known about the development of new‐onset asthma in CRS, particularly in the context of comorbid AR. This study assessed the impact of CRS and AR on
Austin J. Lee, Mohamad R. Chaaban
wiley   +1 more source

Nonlinear association between blood eosinophil counts and clinical outcomes in ICU-Admitted patients with acute exacerbation of COPD: a retrospective observational study

BMC Pulmonary Medicine
Background This retrospective cohort study aimed to examine the association between blood eosinophil counts and in-hospital mortality among patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) admitted to the intensive care ...
Rundi Gao, Suqun Zheng, Xiao Shen, Liying Xu, Huihua Hong   +4 more
doaj   +1 more source

Clinical Characteristics of Eosinophilic Chronic Rhinosinusitis with Nasal Polyps in Adolescents

Journal of Asthma and Allergy, 2023
Chien-Chia Huang,1,2 Po-Hung Chang,1,* Yen-Lin Huang,3– 5 Ta-Jen Lee,1,2,6 Chi-Che Huang,1,2 Pei-Wen Wu1,2,* 1Division of Rhinology, Department of Otolaryngology, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan; 2School of
Huang CC, Chang PH, Huang YL, Lee TJ, Huang CC, Wu PW   +5 more
doaj  

Eosinophil Depletion with Benralizumab for Eosinophilic Esophagitis

New England Journal of Medicine
Benralizumab is an eosinophil-depleting anti-interleukin-5 receptor α monoclonal antibody. The efficacy and safety of benralizumab in patients with eosinophilic esophagitis are unclear.In a phase 3, multicenter, double-blind, randomized, placebo-controlled trial, we assigned patients 12 to 65 years of age with symptomatic and histologically active ...
Marc E Rothenberg 1, Evan S Dellon 1, Margaret H Collins 1, Albert J Bredenoord 1, Ikuo Hirano 1, Kathryn A Peterson 1, Laura Brooks 1, Julie M Caldwell 1, Harald Fjällbrant 1, Hanna Grindebacke 1, Calvin N Ho 1, Matthew Keith 1, Christopher McCrae 1, Dominic Sinibaldi 1, Wendy I White 1, Catherine J Datto 1, MESSINA Trial Investigators: Fabio Almerigogna, Ignacio Antepara Ercoreca, Ana María Alonso Llamazares, Laurent Alric, Dhandapani Ashok, Kevin Bax, Lindsey McLeish, María Basagaña Torrentó, Amir Ben Tov, Adi Anafy, Dmitry S Bordin, Elen R Valitova, Albert J Bredenoord, M Laura Haasnoot, Aaltje Lei, Marco Caminati, Mirna Chehade, Constanza Ciriza de Los Ríos, Steven Clayton, Anca Mihaela Safta, Prerana Williamson, Elżbieta Czkwianianc, Wit Danilkiewicz, Nicola De Bortoli, Santino Marchi, Evan Dellon, Anjan Dhar, Rafael Firszt, Natalia Filipof, Ronald Fogel, Yasuhiro Fujiwara, Beata Gawdis-Wojnarska, Maciej Gonciarz, Nirmala Gonsalves, Frédéric Gottrand, Matthieu Antoine, Ian M Gralnek, Matthieu Groh, Catherine Nizou, Mar Guilarte Clavero, Laura Company-Sapiña, Ingrid Johana Gil, Paula Galván-Blasco, Thirumazhisai Gunasekaran, Jamal Hayat, Samantha Baillie, Attah Ocholi, Abigail Seward, Enrico Heffler, Alessandro Repici, Gaia Pellegatta, Francesca Racca, Navneet Hundal, Norihisa Ishimura, Eiko Okimoto, Anand S Jain, Halley Fowler, Maria Janiak, Jayaprakash Kamath, Showkat Hossain, Sergey Kashin, Jun Kato, Sibylle Koletzko, Hannes Leon, Tobias Schwerd, Bartosz Korczowski, Michał Korczowski, Natalya Krasnopeeva, Santhosh Kumar, Guillaume Lefevre, Jaroslaw Leszczyszyn, John Leung, Evan Cunningham, Joel Liem, Lindsay Douglas, Tracey Bondy, Delina Copland, Amanda Vieira, Maxime Luu, Kristle Lee Lynch, Jonathan Matz, François Mion, Sabine Roman, Ziva Mrevlje-Roman, Zdenka Cipinova, Rosa Muñoz-Cano, Gemma Lopez, Jason Ohayon, Sibgha Rehman, Vaidehi Bhatt, Gurnoor Walia, Robert Pesek, Erin Thomas, Safin Attwal, Kathryn Peterson, Amy Holman, Mohammed Mannan, Anupama Ravi, Imad Absah, Puanani Hopson, Yehuda Ringel, Marc Rothenberg, Kara Kliewer, Cristin Murray Petzold, Vincent Mukkada, Phil Putnam, Scott Bolton, Justin Schwartz, Pablo Abonia, Erinn Kellner, Ashley Devonshire, Frederick Ruthardt, Cecilio Santander Vaquero, Sergio Casabona Francés, Teresa Pérez Fernandez, Verónica Martin Domínguez, Pedro Majano Rodriguez, Francisca Molina Jiménez, Jennifer Fernandez Pacheco, Ellen Sher, Gary Gross, Jacqueline Ross, Ulyana Trytko, Peter Siersema, Dareen Siri, María Luisa Somoza Álvarez, Kathrin Sprinzl, Anna Stanziola, Miguel Stein, Robert Szalewski, Vinay Mehta, Alexander Trukhmanov, Vladimir Ivashkin, Tatiana Lapina, Toshio Uraoka, Christoph Schlag, Simon Weidlich, Jörg Ulrich, Bas Weusten, Phillip Woodland, William Yang, Patrizia Zentilin, Manuele Furnari, Elisabetta Giuliana, Giorgia Bodini, Elisa Marabotto, Frank Zerbib, Noam Zevit, Maciej Żymła   +164 more
openaire   +5 more sources

Interspecies Biofilm Dynamics Among Staphylococci: Inflammatory Contributions to Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Introduction Staphylococcus species are frequently isolated from the sinonasal niche of chronic rhinosinusitis (CRS) patients. While Staphylococcus aureus is often associated with recalcitrant CRS, Staphylococcus epidermidis and Staphylococcus lugdunensis are largely deemed commensal.
Sintayehu Ambachew, Mahnaz Ramezanpour, Clare M. Cooksley, Sholeh Feizi, Muhammed Awad, Kevin Aaron Fenix, Peter‐John Wormald, Alkis J. Psaltis, Sarah Vreugde   +8 more
wiley   +1 more source

Comparison of the peripheral blood eosinophil count using near-patient testing and standard automated laboratory measurement in healthy, asthmatic and COPD subjects [PDF]

, 2017
Kirsty Hambleton, Clare M Connolly, Catherine Borg, Joanne H Davies, Helen P Jeffers, Richard EK Russell, Mona Bafadhel Respiratory Medicine Unit, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK Abstract: Near-patient testing
Connolly CM, Russell REK, Borg C, Hambleton K, Bafadhel M, Davies JH, Jeffers HP   +6 more
core