Results 191 to 200 of about 186,812 (342)

Endomyocardial Fibrosis Associated With Hypereosinophilic Syndrome: Diagnostic and Management Insights From a Case Report

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Endomyocardial fibrosis (EMF) is a rare form of restrictive cardiomyopathy associated with eosinophilic disorders, characterized by apical subendocardial fibrosis and thrombus formation. Cardiac magnetic resonance (CMR) provides a comprehensive, noninvasive evaluation, enabling diagnosis, assessment of disease activity, and guidance of therapy.
Ibrahim Antoun, Benjamin Marrow, Ravi Pathmanathan, Sanjay S. Bhandari   +3 more
wiley   +1 more source

Eosinophils and the Efficacy of Immune Checkpoint Inhibitors Across Multiple Cancers: A Retrospective Study. [PDF]

Biomedicines
Suzuki R, Ohkuma R, Watanabe M, Mura E, Tsurui T, Iriguchi N, Ishiguro T, Hirasawa Y, Ikeda G, Shimokawa M, Ariizumi H, Kubota Y, Yoshimura K, Kobayashi S, Tsunoda T, Horiike A, Tsuji M, Kiuchi Y, Oguchi T, Wada S.   +19 more
europepmc   +1 more source

Eosinophils express a functional receptor for interferon alpha: inhibitory role of interferon alpha on the release of mediators [PDF]

, 1996
Delphine Aldebert, Bouchaïb Lamkhioued, Corinne Desaint, AS Gounni, Michel Goldman, A Capron, Lionel Prin, Moníque Capron   +7 more
openalex   +1 more source

Verekitug, a Novel Antibody Antagonist to the TSLP Receptor in Adults with Asthma: A 32‐Week Randomized Phase 1b Multiple Ascending‐Dose Trial

Clinical Pharmacology &Therapeutics, EarlyView.
Verekitug, a novel, high‐affinity, fully human monoclonal antibody targeting thymic stromal lymphopoietin receptor (TSLPR), is in development as a potential treatment for severe asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), and chronic obstructive pulmonary disease (COPD).
Dave Singh, Chaim M. Brickman, Peter Lloyd, Ashish Kalra, Subhabrata Biswas, Arkadeep Sinha, Alex Mulvanny, Sumathi Sivapalasingam, Oren M. Becker, Aaron Deykin   +9 more
wiley   +1 more source

Predictive Value of Blood Eosinophil Ratio for Risk Stratification in Patients With Eosinophilic Chronic Rhinosinusitis With Nasal Polyps. [PDF]

Laryngoscope Investig Otolaryngol
Zuo T, Wang J, Chen Y, Zhao H, Hao Y, Yu H, Zhang Y, Song X.   +7 more
europepmc   +1 more source

Tiotropium inhibits increases in nerve-associated eosinophils following antigen challenge and prevents airway hyperreactivity in a guinea pig model of asthma

, 2015
Kalmia S. Buels
openalex   +1 more source

Eosinophils Regulate Peripheral B Cell Numbers in Both Mice and Humans [PDF]

, 2014
Tina W. Wong, Alfred D. Doyle, James J. Lee, Diane F. Jelinek   +3 more
openalex   +1 more source

Eosinophilic Esophagitis [PDF]

JAMA, 2019
Craig D, Peiris, James A, Tarbox
openaire   +2 more sources

Straight to Phase III: Model‐Informed Approach Speeds Depemokimab Clinical Development in Interleukin‐5‐Driven Diseases

Clinical Pharmacology &Therapeutics, EarlyView.
Straight to Phase III: Model‐informed approach speeds depemokimab clinical development in interleukin‐5‐driven diseases. IL‐5, a key mediator of type 2 inflammation, underlies various diseases, including severe asthma, CRSwNP, EGPA, and HES. Reduction in blood eosinophil count (BEC), a biomarker of IL‐5 activity, is commonly used to evaluate the ...
Chiara Zecchin, Stein Schalkwijk, Isabelle J. Pouliquen, Alienor Berges, Nicholas Bird, Richard Follows, Daren Austin   +6 more
wiley   +1 more source

High Blood Eosinophil Count at Stable State is Not Associated with Airway Microbiota Distinct Profile in COPD

International Journal of COPD
Jeanne-Marie Perotin,1,2 Anaëlle Muggeo,3 Quentin Lecomte-Thenot,3 Audrey Brisebarre,1 Sandra Dury,2 Claire Launois,1,2 Julien Ancel,1,2 Valérian Dormoy,1 Thomas Guillard,3 Gaëtan Deslee1,2 1Université de Reims Champagne-Ardenne, INSERM UMR-S 1250 ...
Perotin JM, Muggeo A, Lecomte-Thenot Q, Brisebarre A, Dury S, Launois C, Ancel J, Dormoy V, Guillard T, Deslee G   +9 more
doaj