Results 221 to 230 of about 186,812 (342)

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source

Baseline and early changes in eosinophil count and neutrophil-to-eosinophil ratio predict outcomes in metastatic renal cell carcinoma treated with nivolumab. [PDF]

Sci Rep
Fiala O, Rejleková K, Buchler T, Študentová H, Poprach A, Vočka M, Hošek P, Kopecký J, Matějů M, Zemánková A, Spisarová M, Tkadlecová M, Priester P, Kouřil J, Lohynská R, Grmelová L, Savka A, Štefániková K, Obertová J, Šiková D, Stránský P, Melichar B, Palacka P.   +22 more
europepmc   +1 more source

Eosinophils in the gastrointestinal tract: how much is normal?

, 2018
Jorge Silva, Pedro Amoroso Canão, Maria Céu Espinheira, Eunice Trindade, Fátima Carneiro, Jorge Amil Dias   +5 more
openalex   +2 more sources

NOD2 and TLR2 ligands trigger the activation of basophils and eosinophils by interacting with dermal fibroblasts in atopic dermatitis-like skin inflammation [PDF]

, 2015
Delong Jiao, Chun Kwok Wong, Huaina Qiu, Jie Dong, Zhe Cai, Man Chu, Kam‐Lun Ellis Hon, Miranda Sin‐Man Tsang, Christopher Wai-Kei Lam   +8 more
openalex   +1 more source

Blood eosinophil guided prednisolone therapy for exacerbations of COPD: a further analysis

European Respiratory Journal, 2014
Mona Bafadhel, L. Davies, P. Calverley, S. Aaron, C. Brightling, I. Pavord   +5 more
semanticscholar   +1 more source

Unveiling CLC as a Central Regulator of Allergic Rhinitis via the CLC‐CCL26/POSTN Axis: An Integrated Bioinformatics and Experimental Study

Flavour and Fragrance Journal, EarlyView.
We unveil that CLC orchestrates the dual role of eosinophil recruitment via CCL26 and tissue remodelling via POSTN in allergic rhinitis, identifying it as a potential therapeutic target. ABSTRACT Allergic rhinitis (AR) is a chronic airway inflammation driven by a type 2 immune response, yet the molecular mechanisms underlying its persistence and tissue
Fanyu Yuan, Yuhan Dong, Zishuo Guo, Xiaodong Zhao, Jian Liu, Fangyuan Zhu, Shengjie Ge, Chengcheng Liu, Shuai Xu, Ming Xia   +9 more
wiley   +1 more source

Using biomarkers and independent predictors of therapy response to optimize treatment of uncontrolled severe asthma in the biologic era. [PDF]

Front Allergy
Yasui H.
europepmc   +1 more source

Comparative evaluation of eosinophils in normal mucosa, dysplastic mucosa and oral squamous cell carcinoma with hematoxylin-eosin, Congo red, and EMR1 immunohistochemical staining techniques.

, 2015
Neda Kargahi, Sayyed Mohammad Razavi, Parviz Deyhimi, Solmaz Homayouni   +3 more
openalex   +2 more sources

Human eosinophils express transforming growth factor alpha. [PDF]

, 1990
David T. Wong, Peter F. Weller, Stephen J. Galli, A Elovic, T H Rand, George Gallagher, T Chiang, Ming‐Yung Chou, K Matossian, J McBride   +9 more
openalex   +1 more source

Multi‐Cohort Analysis Reveals Genetic Predispositions to Clonal Hematopoiesis as Mutation‐Specific Risk Factors for Stroke

Advanced Genetics, Volume 6, Issue 1, March 2025.
This study comprehensively evaluated the differential effect of clonal hematopoiesis (CH) mutations on the risk of various stroke subtypes and functional recovery. It shows that TET2 is associated with small vessel stroke possibly via a pro‐inflammatory pathway. Abstract Recent observational studies have found an association between Clonal Hematopoesis
Shuyang Lin, Yang E. Li, Yan Wang
wiley   +1 more source