Results 221 to 230 of about 123,808 (307)

Achieving clinical and histologic remission with tezepelumab in an adolescent with refractory eosinophilic gastrointestinal disease: A case report

JPGN Reports, EarlyView.
Abstract Tezepelumab is a human monoclonal antibody that binds to human thymic stromal lymphopoietin (TSLP), an epithelial cytokine that plays a role in Type 2 signaling. We describe a 17‐year‐old with a history of eosinophilic esophagitis (EoE) and eosinophilic gastroenteritis who demonstrated response to tezepelumab with both clinical and histologic ...
Destiny Newsome, Colby Sharlin, Cindy Salm Bauer, Shauna Schroeder   +3 more
wiley   +1 more source

An Evolving Clinical Phenotype Preceding the Diagnosis of Eosinophilic Granulomatosis With Polyangiitis: A Case Report. [PDF]

Cureus
Knowles M, Leung PHT, Chandran S.
europepmc   +1 more source

Suspected fibrosing cholestatic hepatitis in an immunocompetent child with hepatitis C: Case report

JPGN Reports, EarlyView.
Abstract A 12‐year‐old boy presented to our center with elevated aminotransferases, jaundice, right upper quadrant tenderness, and hepatomegaly. Evaluation revealed a highly elevated blood hepatitis C virus (HCV) ribonucleic acid (RNA) level, and liver biopsy showed canalicular and intrahepatic cholestasis, feathery degeneration of hepatocytes, and ...
Sara Bohon, Regino Gonzalez‐Peralta, Robert J. Fontana, Richard Cordle, Robin LeGallo, Frank DiPaola   +5 more
wiley   +1 more source

Early recognition of eosinophilic granulomatosis with polyangiitis in outpatient settings: musculoskeletal and gastrointestinal clues beyond respiratory disease. [PDF]

Front Immunol
Aitella E, De Martinis M, Ginaldi L.
europepmc   +1 more source

Novel variant and enteroendocrine hormone deficiency in a patient with proline and glutamate‐rich protein with a coiled coil domain 1 (PERCC1) associated enteropathy: New diagnostic and therapeutic insights

JPGN Reports, EarlyView.
Abstract Proline and glutamate‐rich protein with a coiled coil domain 1 (PERCC1)‐associated enteropathy is a rare monogenic congenital diarrhea due to defective enteroendocrine cells (EECs). We describe a 6‐year‐old female with intestinal failure since birth.
Teresa Di Chio, Daniela Gattini, Christina Belza, Iram Siddiqui, Bolette Hartmann, Meghan Zoe Benchimol, Shiqi Zhang, Neil E. Warner, Aleixo M. Muise, Yaron Avitzur   +9 more
wiley   +1 more source

Eosinophil Proportion May Serve as a Candidate Biomarker for Adverse Events in Patients With Urothelial Carcinoma Treated With Enfortumab Vedotin. [PDF]

Cancer Med
Odagiri K, Morikawa T, Naiki T, Sugiyama Y, Tasaki Y, Mimura Y, Naiki-Ito A, Nagai T, Etani T, Iida K, Ishikawa D, Noda Y, Shimizu N, Aoki M, Gonda M, Banno R, Kubota H, Ando R, Umemoto Y, Kawai N, Furukawa-Hibi Y, Yasui T.   +21 more
europepmc   +1 more source

Two pediatric type II achalasia cases complicated by candidal and eosinophilic esophagitis: Successful peroral endoscopic myotomy treatment

JPGN Reports, EarlyView.
Abstract Achalasia is a rare esophageal motility disorder in children, often leading to delayed diagnosis. We report the first two pediatric cases treated with peroral endoscopic myotomy (POEM) at our center, both classified as type II achalasia and complicated by mucosal disease. A 15‐year‐old girl presented with progressive dysphagia and weight loss,
Fabio Rotondo, Antonio Marseglia, Anna Locatelli, Dalila Tedeschi, Marco Gentile, Francesco Perri, Maria Rosa Pastore, Massimo Pettoello Mantovani   +7 more
wiley   +1 more source

Distinct miRNA expression patterns in circulating eosinophil subtypes and their subtype-derived exosomes in allergic asthma. [PDF]

Inflamm Res
Vasyle E, Januskevicius A, Rimkunas A, Palacionyte J, Miliauskas S, Malakauskas K.   +5 more
europepmc   +1 more source

Collagenous gastritis in pediatric patients with severe follicular pangastritis and iron deficiency anemia

JPGN Reports, EarlyView.
Abstract Collagenous gastritis is a rare disorder characterized by subepithelial collagen deposition in the gastric mucosa and is frequently associated with iron deficiency anemia. We report two girls aged 8 and 16 years with persistent iron deficiency anemia, abdominal pain, bloating, and constipation.
María Juliana Rusinque Del Busto, Karina Lozano Rivera, Maira Alejandra Forero Rivera, Alejandra Calderón, Santiago Walker, Angie Vergara Espitia, José Fernando Vera Chamorro   +6 more
wiley   +1 more source