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Survival prediction in stage II/III rectal cancer: Role of immune-inflammatory biomarkers post neoadjuvant chemoradiotherapy. [PDF]
Oncol LettLi B +6 more
europepmc +1 more source
Eosinophil Knockout Humans: Uncovering the Role of Eosinophils Through Eosinophil-Directed Biological Therapies [PDF]
Annual Review of Immunology, 2021 The enigmatic eosinophil has emerged as an exciting component of the immune system, involved in a plethora of homeostatic and inflammatory responses. Substantial progress has been achieved through experimental systems manipulating eosinophils in vivo ...
Albert Bredenoord +2 more
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Annual Review of Immunology, 2006
Eosinophils have been considered end-stage cells involved in host protection against parasites. However, numerous lines of evidence have now changed this perspective by showing that eosinophils are pleiotropic multifunctional leukocytes involved in initiation and propagation of diverse inflammatory responses, as well as modulators of innate and ...
Marc E, Rothenberg, Simon P, Hogan
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Eosinophils have been considered end-stage cells involved in host protection against parasites. However, numerous lines of evidence have now changed this perspective by showing that eosinophils are pleiotropic multifunctional leukocytes involved in initiation and propagation of diverse inflammatory responses, as well as modulators of innate and ...
Marc E, Rothenberg, Simon P, Hogan
openaire +2 more sources
Eosinophilic Gastroenteritis or Eosinophilic Chloroma?
Acta Haematologica, 2004Granulocytic sarcoma of the small intestine preceding or as the presenting feature of acute myelogenous leukemia with chromosome 16 abnormalities has been observed in at least 4 patients. We report the case of a patient initially diagnosed with eosinophilic gastroenteritis, responding to corticosteroid treatment for 21 months and eventually ...
A, Julia, J F, Nomdedeu
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Targeting Eosinophils in Eosinophilic Granulomatosis with Polyangiitis
New England Journal of Medicine, 2017Eosinophilic granulomatosis with polyangiitis, first described in the early 1950s by Dr. Jacob Churg and Dr. Lotte Strauss (hence the original name, the Churg–Strauss syndrome), is a rare condition that can affect many organ systems, most commonly the lung, with the majority of patients presenting with asthma symptoms, occasionally complicated by the ...
Djukanović, Ratko, O'Byrne, Paul
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2014
In 1846, T. Wharton-Jones described a coarsely granular stage in the development of granulocytic cells in animal and human blood. Shortly thereafter, Max Schultze redefined the coarsely granular cells as a type distinct from finely granular cells, rather than just a developmental stage.
Susanne Radonjic-Hösli, Hans-Uwe Simon
openaire +3 more sources
In 1846, T. Wharton-Jones described a coarsely granular stage in the development of granulocytic cells in animal and human blood. Shortly thereafter, Max Schultze redefined the coarsely granular cells as a type distinct from finely granular cells, rather than just a developmental stage.
Susanne Radonjic-Hösli, Hans-Uwe Simon
openaire +3 more sources
Eosinophilic Cationic Protein in Chronic Eosinophilic Pneumonia and Eosinophilic Granuloma
Chest, 1994We measured eosinophilic cationic protein (ECP) concentrations in the circulation and bronchoalveolar lavage (BAL) fluids from patients with chronic eosinophilic pneumonia, patients with eosinophilic granuloma, and normal control subjects. Significantly increased ECP concentrations were found in the circulation of patients with chronic eosinophilic ...
N, Shijubo +4 more
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Annals of Internal Medicine, 2003
Eosinophilic esophagitis is a new disease commonly confused with gastroesophageal reflux disease. Because of different treatments, recognition of eosinophilic esophagitis is important.Recent work further characterizes the allergic response, demonstrating a population of eosinophils different from gut and blood that specifically homes to the esophagus ...
openaire +6 more sources
Eosinophilic esophagitis is a new disease commonly confused with gastroesophageal reflux disease. Because of different treatments, recognition of eosinophilic esophagitis is important.Recent work further characterizes the allergic response, demonstrating a population of eosinophils different from gut and blood that specifically homes to the esophagus ...
openaire +6 more sources