Results 91 to 100 of about 67,658 (263)
The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li +4 more
wiley +1 more source
ABSTRACT Purpose The rising prevalence of obesity introduces challenges in surgical contexts, including endoscopic sinus surgery (ESS) for chronic rhinosinusitis with nasal polyps (CRSwNP). However, the impact of obesity on ESS outcomes remains underexplored. This study aims to evaluate the association between obesity and surgical complexity, operative
Hen Chaushu +6 more
wiley +1 more source
Introduction: Bullous pemphigoid (BP) is an autoimmune disease involving the sub-epidermal layer. Eosinophilia may play a role in the pathogenesis of BP.
Bahareh Abtahi-Naeini +7 more
doaj +1 more source
ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng +3 more
wiley +1 more source
Generalized Eosinophilia Following Moderna COVID-19 Vaccine Administration: Comment [PDF]
Amnuay Kleebayoon, Viroj Wiwanitkit
openalex +1 more source
Research Progress on Upper Airway Cough Syndrome
ABSTRACT Upper airway cough syndrome (UACS) has been identified as a significant contributor to chronic cough in various national guidelines. However, the complexity of its pathogenesis, the lack of clarity surrounding its diagnostic criteria, and its overlap with other etiologies of chronic cough present considerable challenges in both diagnosis and ...
Wan‐Ting Huang, Jia Chen
wiley +1 more source
Eosinophilia and Platelet Derived Growth Factor Receptor A Overexpression in Juvenile Polyps [PDF]
Dina Sweed +6 more
openalex +1 more source
Role for Complement C5 in Eosinophilic Inflammation of Severe Asthma
Complement activation module, particularly C5, is positively associated with eosinophilic inflammation in severe asthma cohorts. Elevated C5 expression correlates with poor lung function improvement and persistent eosinophilic inflammation. Mouse model studies confirm that C5 exacerbates eosinophilic inflammation, highlighting its potential as a ...
Cong Dong +217 more
wiley +1 more source

