Cytogenetically cryptic ZMYM2-FLT3 and DIAPH1-PDGFRB gene fusions in myeloid neoplasms with ...
M. Jawhar+17 more
semanticscholar +1 more source
Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification. [PDF]
Since 2013, the International Union of Immunological Societies (IUIS) expert committee (EC) on Inborn Errors of Immunity (IEI) has published an updated phenotypic classification of IEI, which accompanies and complements their genotypic classification ...
Ailal, Fatima+18 more
core
Cellular and humoral immune responses and protection against schistosomes induced by a radiation-attenuated vaccine in chimpanzees [PDF]
The radiation-attenuated Schistosoma mansoni vaccine is highly effective in rodents and primates but has never been tested in humans, primarily for safety reasons.
Abe K.+65 more
core +2 more sources
Eosinophilia and clinical outcome of chronic obstructive pulmonary disease: a meta-analysis
Numerous studies have investigated the association between eosinophilia and clinical outcome of patients with chronic obstructive pulmonary disease (COPD) but the evidence is conflicting.
J. Ho+15 more
semanticscholar +1 more source
The use of drug calendars for the diagnosis of cutaneous drug eruptions in the age of electronic medical records [PDF]
A morbilliform drug eruption is the most common condition leading to a dermatology consultation for a patient in the hospital. Timing is an important diagnostic tool since the onset of a skin rash usually takes place within days-to-weeks of the start of ...
Cohen, Philip R, Grossman, Marc E
core
Eosinophils Are Important for Protection, Immunoregulation and Pathology during Infection with Nematode Microfilariae [PDF]
Eosinophil responses typify both allergic and parasitic helminth disease. In helminthic disease, the role of eosinophils can be both protective in immune responses and destructive in pathological responses. To investigate whether eosinophils are involved
AA Humbles+52 more
core +3 more sources
Investigating Airway Symptoms in Eosinophilic Esophagitis (EoE)
ABSTRACT Objectives Diagnostic delay of eosinophilic esophagitis (EoE) is significant, and efforts are needed to raise awareness and reduce prolonged symptoms and complications. Airway and swallowing symptoms often overlap, especially in children, complicating diagnosis and increasing delays.
Angela Huynh+6 more
wiley +1 more source
Chronic rhinosinusitis (CRS) can be classified according to the presence of a nasal polyp (NP): CRS with NP (CRSwNP) and CRS without NP (CRSsNP). CRSwNP has characteristics with high infiltration of tissue eosinophilia with a burst of Th2 inflammatory ...
Sung-Woo Cho+4 more
semanticscholar +1 more source
Pulmonary effects of inhalation of spark-generated silver nanoparticles in Brown-Norway and Sprague-Dawley rats [PDF]
The increasing use of silver nanoparticles (AgNPs) in consumer products is concerning. We examined the potential toxic effects when inhaled in Brown-Norway (BN) rats with a pre-inflammatory state compared to Sprague-Dawley (SD) rats.We determined the ...
Buckley, A+17 more
core +1 more source
Feasibility of Treating Eosinophilic Chronic Rhinosinusitis Using Short‐Chain Fatty Acids
Epithelial cell‐derived cytokines including thymic stromal lymphopoietin (TSLP) are important in the pathogenesis of chronic rhinosinusitis with nasal polyps. We demonstrate the inhibitory effect of TSLP production in airway epithelial cells and eosinophil survival by short‐chain fatty acids (SCFAs) as a potential new strategy to reduce nasal polyps ...
Rikako Gozawa+12 more
wiley +1 more source