Results 371 to 380 of about 270,393 (395)
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Eosinophil Depletion with Benralizumab for Eosinophilic Esophagitis
New England Journal of MedicineBenralizumab is an eosinophil-depleting anti-interleukin-5 receptor α monoclonal antibody. The efficacy and safety of benralizumab in patients with eosinophilic esophagitis are unclear.In a phase 3, multicenter, double-blind, randomized, placebo-controlled trial, we assigned patients 12 to 65 years of age with symptomatic and histologically active ...
Marc E Rothenberg 1 +164 more
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Eosinophilic Cationic Protein in Chronic Eosinophilic Pneumonia and Eosinophilic Granuloma
Chest, 1994We measured eosinophilic cationic protein (ECP) concentrations in the circulation and bronchoalveolar lavage (BAL) fluids from patients with chronic eosinophilic pneumonia, patients with eosinophilic granuloma, and normal control subjects. Significantly increased ECP concentrations were found in the circulation of patients with chronic eosinophilic ...
Noriharu Shijubo +4 more
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Eosinophilic esophagitis: A subset of eosinophilic gastroenteritis
Current Gastroenterology Reports, 1999Eosinophilic gastroenteritis (EG) was first described over 50 years ago. Despite its long history, it remains an ill-defined and poorly understood entity. EG can present in a number of ways, none of which are exclusive to the disorder. EG has features of allergy and immune dysregulation but does not clearly fit into the category of allergic or immune ...
Chris A. Liacouras +1 more
openaire +2 more sources
Arthritis & Rheumatology, 2020
To describe the efficacy and safety of biologics for the treatment of eosinophilic granulomatosis with polyangiitis (EGPA).
Alice Canzian +37 more
semanticscholar +1 more source
To describe the efficacy and safety of biologics for the treatment of eosinophilic granulomatosis with polyangiitis (EGPA).
Alice Canzian +37 more
semanticscholar +1 more source
Clinical and Experimental Allergy, 2020
Anti‐interleukin‐5 (IL‐5) monoclonal antibodies can be used as add‐on biological therapies in allergic and non‐allergic patients with severe eosinophilic asthma. However, within such a therapeutic context real‐life investigations are lacking.
C. Pelaia +7 more
semanticscholar +1 more source
Anti‐interleukin‐5 (IL‐5) monoclonal antibodies can be used as add‐on biological therapies in allergic and non‐allergic patients with severe eosinophilic asthma. However, within such a therapeutic context real‐life investigations are lacking.
C. Pelaia +7 more
semanticscholar +1 more source
Heterogeneity of Eosinophils in Chronic Eosinophilic Pneumonia
International Archives of Allergy and Immunology, 1996It has previously been shown that patients with chronic eosinophilic pneumonia can be divided into 2 groups according to the chemotactic response of their eosinophils to 5 different eosinophil chemotactic factors (ECFs) and laboratory findings. In contrast, eosinophils obtained by bronchoalveolar lavage from both groups responded to all 5 ECFs.
Hirotsugu Kohrogi +6 more
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Eosinophilic cellulitis and eosinophilic pustular folliculitis
Journal of the American Academy of Dermatology, 1989This report describes a patient with a drug reaction and histologic changes of both eosinophilic cellulitis and eosinophilic pustular folliculitis. We propose that some cases of eosinophilic pustular folliculitis, like eosinophilic cellulitis, may occur as a result of a hypersensitivity phenomenon.
Wilma F. Bergfeld +4 more
openaire +3 more sources
1993
Cytokines act on eosinophils to regulate eosinophil function, with IL-5 recognised to be especially important in control of eosinopoiesis, eosinophil survival and eosinophil priming. In addition, eosinophils have the capacity to produce cytokines involved in acute and chronic inflammatory and repair processes, as well as to produce cytokines that ...
I J De Vries +6 more
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Cytokines act on eosinophils to regulate eosinophil function, with IL-5 recognised to be especially important in control of eosinopoiesis, eosinophil survival and eosinophil priming. In addition, eosinophils have the capacity to produce cytokines involved in acute and chronic inflammatory and repair processes, as well as to produce cytokines that ...
I J De Vries +6 more
openaire +3 more sources
Activated Eosinophils in Familial Eosinophilic Gastroenteritis
Gastroenterology, 1985Two siblings with eosinophilic gastroenteritis who presented with severe iron deficiency anemia and hypoalbuminemia associated with varying degrees of mucosal damage are described. Using a monoclonal antibody to the secreted form of eosinophil cationic protein, we demonstrated activated degranulating eosinophils in the gastrointestinal mucosa that ...
P-C. Tai +6 more
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Pediatric Clinics of North America, 2019
Eosinophilic esophagitis is a recently defined condition that has dramatically increased in prevalence in the last several decades. It may occur at any age, but the clinical presentation in young children is often more vague than the classic solid food dysphagia and food impacting that are the major presenting symptoms of eosinophilic esophagitis in ...
Heather K, Lehman, Weyman, Lam
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Eosinophilic esophagitis is a recently defined condition that has dramatically increased in prevalence in the last several decades. It may occur at any age, but the clinical presentation in young children is often more vague than the classic solid food dysphagia and food impacting that are the major presenting symptoms of eosinophilic esophagitis in ...
Heather K, Lehman, Weyman, Lam
openaire +3 more sources