Therapeutic Advances in Respiratory Disease, 2021 Background: Severe eosinophilic asthma is frequently associated to chronic rhinosinusitis and nasal polyposis (CRSwNP) that contribute to poor asthma control.
Aikaterini Detoraki +11 more
semanticscholar +1 more source
Efficacy of Dupilumab in a Phase 2 Randomized Trial of Adults With Active Eosinophilic Esophagitis.
Gastroenterology, 2019 BACKGROUND & AIMS Eosinophilic esophagitis (EoE) is an allergen-mediated inflammatory disease with no approved treatment in the United States. Dupilumab, a VelocImmune-derived human monoclonal antibody against the interleukin 4 (IL4) receptor, inhibits ...
I. Hirano +20 more
semanticscholar +1 more source
Differences in Clinical and Immunological Characteristics According to the Various Criteria for Tissue Eosinophilia in Chronic Rhinosinusitis With Nasal Polyps [PDF]
Clinical and Experimental Otorhinolaryngology, 2023 Objectives Several criteria exist for classifying chronic rhinosinusitis with nasal polyps (CRSwNP) as eosinophilic or non-eosinophilic. This study attempted to evaluate several criteria for defining eosinophilic CRSwNP from clinical and immunological ...
Seung Koo Yang +5 more
doaj +1 more source
Reslizumab in patients with inadequately controlled late-onset asthma and elevated blood eosinophils [PDF]
, 2017 INTRODUCTION: Asthma with adult onset and elevated blood eosinophils is a difficult-to-treat subgroup. This post hoc analysis evaluated reslizumab, an anti-interleukin-5 monoclonal antibody, in patients with late-onset eosinophilic asthma.
Brusselle, Guy +3 more
core +2 more sources
Report of results of pleural biopsy (Needle biopsy and open biopsy) in 108 cases and 245 biopsies [PDF]
, 1960 1. The results of 245 pleural biopsies perfomed in 108 patients including 219 pleural needle biopsies and 26 pleural open biopsies were reported. The method of pleural biopsy seems to be superior to any other currently available diagnostic procedures for
Mc, Lt. Col., Sohn, Isaack
core +1 more source
Novel mechanisms of action contributing to benralizumab's potent anti-eosinophilic activity
European Respiratory Journal, 2021 Background Benralizumab is a humanised, anti-interleukin-5 receptor α monoclonal antibody with anti-eosinophilic activity. Lack of fucose (afucosylation) increases its affinity to CD16a and significantly enhances antibody-dependent cell-mediated ...
R. Dagher +8 more
semanticscholar +1 more source
Pneumatosis Coli Secondary to Eosinophilic Colitis: Report of a Refractory Case [PDF]
Iranian Journal of Colorectal Research, 2016 Introduction Pneumatosis intestinalis (PI) is a broad term that describes the presence of gas in the bowel walls. The colon is affected in 36% of cases.
Sameh Hany Emile +2 more
doaj +1 more source
Death Resulting from Pneumocephalus Complicating Endoscopic Food Bolus Retrieval in a Patient with Eosinophilic Esophagitis [PDF]
, 2016 Pneumocephalus is a rare complication of esophagogastroduodenoscopy (EGD), but existing literature does not discuss pneumocephalus surrounding endoscopic food bolus retrieval.
Fuhs, Amy K., Prahlow, Joseph A.
core +1 more source
Eosinophilic Asthma: Pathophysiology and Therapeutic Horizons
CellsAsthma is a prevalent chronic non-communicable disease, affecting approximately 300 million people worldwide. It is characterized by significant airway inflammation, hyperresponsiveness, obstruction, and remodeling.
Musaddique Hussain, Gang Liu
semanticscholar +1 more source
Allergy, 2005 Eosinophilic pneumonias (EP) encompass a wide spectrum of lung diseases characterized by peripheral blood eosinophilia (>1 × 109 eosinophils/l) and/or alveolar eosinophilia (>25%). Blood eosinophilia may be lacking, as in the early phase of idiopathic acute EP, or in patients already taking oral corticosteroids.
Cottin, Vincent, Cordier, Jean-François
openaire +4 more sources