Results 81 to 90 of about 212,365 (347)
Advanced Science, EarlyView.Polyvinyl chloride (PVC) nanoplastics (NPs) are shown to aggravate allergic airway inflammation in asthma by triggering R‐loop accumulation and activating the cGAS‐STING pathway in macrophages. This study reveals a novel immunotoxic mechanism linking environmental plastic exposure to asthma pathogenesis and highlights potential molecular targets for ...
Qimei Bao +16 more
wiley +1 more source
Diagnosis and management of eosinophilic asthma: a US perspective. [PDF]
, 2014 Eosinophilic asthma is now recognized as an important subphenotype of asthma based on the pattern of inflammatory cellular infiltrate in the airway. Eosinophilic asthma can be associated with increased asthma severity, atopy, late-onset disease, and ...
Doherty, Taylor A, Walford, Hannah H
core +1 more source
Clinical Microbiology Reviews, 2012 SUMMARY This review starts with discussions of several infectious causes of eosinophilic pneumonia, which are almost exclusively parasitic in nature. Pulmonary infections due specifically to Ascaris , hookworms, Strongyloides , Paragonimus , filariasis, and
Akuthota, P., Weller, Peter
openaire +3 more sources
Advanced Science, EarlyView.Employing snRNA‐seq post‐MCAO‐induced retinal ischemia (RI), this study revealed a novel Hmga2‐high Müller cell subpopulation. Hmga2 knockout alleviated neuroinflammation and RI symptoms, potentially by binding PI3K and regulating Müller cell autophagy.
Weihao Lv +11 more
wiley +1 more source
Biodegradability and tissue reaction of random copolymers of L-leucine, L-aspartic acid, and L-aspartic acid esters [PDF]
, 1977 A series of copoly(α-amino acids) with varying percentages of hydrophilic (l-aspartic acid) and hydrophobic monomers (l-leucine, ß-methyl-l-aspartate, and ß-benzyl-l-aspartate) were implanted subcutaneously in rats and the macroscopic degradation ...
Bantjes, A. +4 more
core +3 more sources
Effects of arginine and ornithine supplementation to a high‐protein diet on selected cellular immune variables in adult cats [PDF]
, 2020 Background: Dietary protein and amino acid intake and composition can modulate immune function. Objectives: To evaluate the effects of high‐protein intake and arginine and ornithine supplementation on feline immune cells.
Kohn, Barbara +2 more
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The Pathogenesis of Eosinophilic Esophagitis: Beyond the Eosinophil [PDF]
Digestive Diseases and Sciences, 2013 Over the past two decades, eosinophilic esophagitis (EoE) has undergone a remarkable transformation. What used to be a rare, case-reportable condition about which little was known, is now widely recognized as an important cause of upper GI morbidity and the subject of intense research activity.
openaire +3 more sources
Advanced Science, EarlyView.In this work, “inorganic‐free” nanosheets, named PNSE are developed using template‐based synthesis technology. The functionalized organic nanosheets exhibit low cytotoxicity, mild protein adsorption, and potent binding efficacy to epithelial sEVs.
Zhaoxu Tu +11 more
wiley +1 more source
A case of eosinophilic gastroenteritis with eosinophilic ascites.
Nihon Naika Gakkai Zasshi, 1989 48才の女性が,水様性下痢便に続く著明な腹水で,近医より紹介された.末梢血白血球分画で好酸球が42%と著増を示し,また,腹水中の好酸球が84%を占めていた.開腹による小腸楔状切除生検にて,粘膜下層から漿膜下層にわたるほぼ全層に,好酸球の浸潤を認めた.これらから,本例はいわゆるMcNabbらの言うtransmural eosinophilic gastroenteritis with ascitesに相当すると思われる.
Mitsuya Harigane +5 more
openaire +4 more sources
Advanced Science, EarlyView.Histamine H4 receptor (H4R) antagonist VUF6002 mimics low‐dose X‐ray irradiation in aged Alzheimer's disease (AD) mice, enhancing microglial clearance of amyloid‐beta/hyperphosphorylated tau aggregates and restoring cognition. Microglial H4R deletion activates cAMP/TGF‐β1/Smad3 pathway, enhancing phagocytosis, while TGF‐β receptor 1 deletion abolishes ...
Yi‐Jun Xu +5 more
wiley +1 more source