Results 121 to 130 of about 1,674,898 (231)

Increase of high mobility group box chromosomal protein 1 in eosinophilic chronic rhinosinusitis with nasal polyps

, 2014
Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by eosinophil-dominant infiltration in Europe and the United States. However, CRSwNP in Asia has shown different immunopathologic features.
Lei Chen, Mao, Mingfeng, Daishi Chen, Chen, Lei, Luisa M. Bellussi, Mingfeng Mao, Desiderio Passali, Bellussi, Luisa M, Passali, Desiderio, Chen, Daishi   +9 more
core   +1 more source

Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases

Allergy, EarlyView.
ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz, Salvador Iborra, Carlos Blanco, Ruperto González‐Pérez, Emilio Nuñez‐Borque, Can Zeyneloglu, Huseyn Babayev, Ozlem Göksel, Tuncay Göksel, Musa Khaitov, Dmitry Kudlay, Yadong Gao, Mustafa Sevim, Marie‐Charlotte Brüggen, Oral Alpan, Ming Wang, Luo Zhang, María J. Torres, Mohamed Shamji, Mübeccel Akdis, Kari C. Nadeau, Ismail Ogulur, Cezmi A. Akdis   +22 more
wiley   +1 more source

Resection versus preservation of anterior end of middle turbinate in eosinophilic chronic rhinosinusitis

The Egyptian Journal of Otolaryngology
Background Eosinophilic chronic rhinosinusitis (eCRS) is a subtype of chronic rhinosinusitis with nasal polyps (CRSwNP), characterized by significant eosinophilic inflammation, although type 2 eosinophilic inflammation can also be identified in CRS ...
Lana Azad, Muaid I. Aziz Baban, Haval Ahmed Hama, Shang Qaraman Qadir Zangana, Aros Bestun Saeed, Shkar Nawzad Omer, Ahmed Muayad, Hwshyar Ali Ahmed, Goran M. Raouf Abdulqader, Paolo Castelnuovo   +9 more
doaj   +1 more source

Emerging Paediatric Uses of Dupilumab Beyond Approvals

Clinical &Experimental Allergy, EarlyView.
Dupilumab, through IL‐4Rα blockade, shows promising efficacy beyond approved indications in paediatric diseases driven by T2 inflammation. Emerging evidence—mainly from small studies—supports improvements in disease severity and quality of life, highlighting its potential as a targeted, steroid‐sparing therapy while underscoring the need for ...
Simone Foti Randazzese, Anna Calamita, Diletta D'Angelo, Alessia Marseglia, Esther Mesa Lombardero, Sara Pedersoli, Micol Tedeschi, Mara De Amici, Sara Manti, Valeria Brazzelli, Amelia Licari, Gian Luigi Marseglia   +11 more
wiley   +1 more source

Predicting revision sinus surgery in allergic fungal and eosinophilic mucin chronic rhinosinusitis

, 2017
Chronic rhinosinusitis consists of several disease processes. Eosinophilic mucin is found in the subtypes of allergic fungal sinusitis (AFS) and eosinophilic mucin chronic rhinosinusitis (EMCRS).
Ahmed, Jamal, Jamal Ahmed, Younis, Ramzi T, Ramzi T. Younis   +3 more
core   +1 more source

Comparison of olfactory and taste functions between eosinophilic and non-eosinophilic chronic rhinosinusitis

, 2020
Objective: Most patients with chronic rhinosinusitis (CRS) complain of olfactory and/or taste dysfunctions. However, olfactory and taste dysfunctions depending on the subtype of CRS, classified as eosinophilic CRS (ECRS) and non-eosinophilic CRS (NCRS ...
윤주헌, 하종균, 김창훈, 조형주   +3 more
core   +1 more source

Manuka Honey Sinus Irrigation Versus Systemic Itraconazole in Allergic Fungal Rhinosinusitis: Randomised Clinical Trial for Efficacy and Safety

Clinical Otolaryngology, EarlyView.
ABSTRACT Background Allergic fungal rhinosinusitis (AFRS) is a persistent sinus condition caused by fungal allergies. Endoscopic sinus surgery (ESS) and postoperative systematic and local medical therapies are the most common treatment protocols. Although oral antifungals such as itraconazole are frequently utilised postoperatively, there is increasing
Khalaf Hamead, Mostafa Ismail, Abdelrahim A. Abdelkarim, Abdelhakim Atef Abdelhakim, Khaled Mohamed Abdelzaher   +4 more
wiley   +1 more source

Eosinophilia and Hypereosinophilia: A Practical Approach to Navigating a Broad Differential Diagnosis

European Journal of Haematology, EarlyView.
ABSTRACT Eosinophilia, defined as an absolute eosinophil count (AEC) of ≥ 0.5 × 109/L, is a frequently encountered finding with a vast spectrum of potential underlying etiologies. Hypereosinophilia (HE) is defined as AEC > 1.5 × 109/L and may become life‐threatening when eosinophil‐induced organ damage occurs, defining the hypereosinophilic syndrome ...
Stijn Wigerinck, Peter Vandenberghe
wiley   +1 more source

Complement–Eosinophil Crosstalk Links Complement Activation to Fibrin Deposition in Eosinophilic Chronic Rhinosinusitis

Allergy, EarlyView.
Ryo Hasegawa, Shigeharu Ueki, Misaki Arima, Shohei Nishiyama, Keinosuke Hizuka, Kohei Tatsumi, Ayako Sawai, Anna Shimizu, Yuki Sonoda, Eiichi Kato, Masanori Kidoguchi, Masafumi Sakashita, Yohei Sato, Atsushi Kato, Bruce K. Tan, Robert C. Kern, Robert P. Schleimer, Shigeharu Fujieda, Yoshimasa Imoto   +18 more
wiley   +1 more source

Clinical Effects of Adjunctive Shoseiryuto Therapy in Refractory Eosinophilic Chronic Rhinosinusitis: A Pilot Retrospective Case Series Focusing on Mucus‐Related Symptoms

Traditional &Kampo Medicine, Volume 13, Issue 3, December 2026.
ABSTRACT Aim To evaluate the efficacy and safety of adjunctive shoseiryuto, a traditional Japanese Kampo medicine, in patients with refractory eosinophilic chronic rhinosinusitis (ECRS), with particular attention to mucus‐related symptoms. Methods This retrospective pilot case series was conducted at Osaka Medical and Pharmaceutical University Hospital
Yusuke Kikuoka
wiley   +1 more source