Results 101 to 110 of about 1,674,898 (231)

Maintenance of memory-type pathogenic Th2 cells in the pathophysiology of chronic airway inflammation

Inflammation and Regeneration, 2018
Background Immunological memory is critical for long-standing protection against microorganisms; however, certain antigen-specific memory CD4+ T helper (Th) cells drive immune-related pathology, including chronic allergic inflammation such as asthma. The
Kiyoshi Hirahara, Kenta Shinoda, Yusuke Endo, Tomomi Ichikawa, Toshinori Nakayama   +4 more
doaj   +1 more source

The Usefulness of Machine Learning Models to Predict Patient‐Reported Outcome Measures in Chronic Rhinosinusitis With Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background and Objective The treatment available for chronic rhinosinusitis with nasal polyps (CRSwNP) has remained unsatisfactory. Patient‐reported outcome measures (PROMs), capturing patient‐perceived health status and well‐being, are vehicles for measuring and improving the efficacy of care.
Yang Shen, Pan‐Hui Xiong, Bo‐Wen Zheng, Chen‐Xi Li, Jun‐Liang Chen, Yue Gu, Yan‐Han Yang, Tao Lu, Yu‐Cheng Yang   +8 more
wiley   +1 more source

Rhinosinusitis Predispose Asthmatic Patients to Severe Bronchial Asthma [PDF]

In this study, we evaluated the relationship between rhinosinusitis to the severity of asthma in asthmatic patients. This cross-sectional study was conducted on 90 patients with asthma referring to Imam Khomeini Hospital in Ardabil city.
غفرانی, محسن, اناری, حسن, اعظمی, احد, حبیب زاده, الهام, شرقی, افشان   +4 more
core   +1 more source

Eosinophilic mucus chronic rhinosinusitis: Clinical subgroups or a homogeneous pathogenic entity?

, 2006
© The American Laryngological, Rhinological & Otological Society, Inc.Background: Eosinophilic mucus chronic rhinosinusitis (EMCRS) can be subclassified using the criteria of detection of fungi in eosinophilic mucus and systemic fungal allergy.
Macardle, P., William B. Smith, Pant, Harshita, MacArdle, Peter James, Harshita Pant, Peter J. Wormald, Kette, F., Frank E. Kette, Kette, Frank E, Peter J. Macardle, Smith, W., Wormald, Peter John, Pant, H., Smith, William B, Wormald, P.   +14 more
core   +1 more source

Current Advances in Spatial Pathology of Nasal Polyps: Challenges, Opportunities for Artificial Intelligence, and Future Directions

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by inflammatory heterogeneity, epithelial hyperplasia, and tissue remodeling, with spatial pathology critical for deciphering pathological mechanisms and guiding clinical practice.
Zi‐Xuan Hua, Xin Luo, Ning Kang, Ze‐Zhi Guo, Man‐Hou Chao, Hua‐Mei Yan, Wan‐Xin Zhang, Tong Wu, Zi‐Qi Zhang, Xue‐Kun Huang, Ya‐Na Zhang, Zhao‐Hui Shi, Qin‐Tai Yang   +12 more
wiley   +1 more source

Personalized Surgery for Allergic Fungal Rhinosinusitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Allergic fungal rhinosinusitis (AFRS) frequently presents as unilateral or asymmetric disease. In cases with minimal disease on one side, the question remains as to the necessary extent of surgery. Objective To determine the relationship between symmetry and clinical characteristics in AFRS patients, with a focus on implications for
Erin E. Briggs, Zachary M. Soler, Asher T. Ripp, Ryan A. Durgham, Shabih H. Jafri, Alexander N. Duffy, Vinay K. Rathi, Rodney J. Schlosser   +7 more
wiley   +1 more source

Generative AI and Clinicians Show Comparable Prognostic Reasoning From Clinical Narratives in Biologic‐Treated CRSwNP

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To compare the ability of large language models (LLMs) and otolaryngologists to identify prognostic signals from brief clinical vignettes in CRSwNP. Methods In this blinded study, 68 adults initiating biologic therapy for CRSwNP (≥ 36 months follow‐up) were represented by standardized vignettes derived from documentation immediately ...
Sholem Hack, Chase Kahn, Ainhoa Garcia‐Lliberos, Cristina Rodriguez‐Prado, Ameen Biadsee, Maxime Fieux, Mark Liu, Eran Glikson, Masayoshi Takashima, Omar G. Ahmed, Raj Sindwani, Dennis M. Tang, Christopher R. Roxbury   +12 more
wiley   +1 more source

Kesesuaian Endotipe dengan Skor Japanese Epidemiological Survey of Refractory Eosinophilic Chronic Rhinosinusitis (JESREC) pada Rinosinusitis Kronik

, 2022
Latar Belakang: Rinosinusitis kronik (RSK) merupakan salah satu penyakit di bidang THT-KL yang masih menjadi beban kesehatan di suatu negara. Selain menurunkan kualitas hidup penderitanya, strategi penatalaksanaan RSK masih merupakan tantangan di ...
Dr. dr. H. Edi Handoko,, Sp. T.H.T.B.K.L. Subsp.Oto.(K),, dr. Iriana Maharani,, Sp. T.H.T.B.K.L. Subsp.Rino.(K), FICS, Christianty, dr. Finna   +2 more
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The Global Airways Unit: A Multidisciplinary Strategy for Early Diagnosis and Comorbidity Detection

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic respiratory diseases impose a large global burden of morbidity, mortality, and cost. The concept of a global airway has become increasingly supported by epidemiologic, mechanistic, and clinical evidence. However, clinical care often remains fragmented between ear, nose, and throat (ENT), allergy, and pulmonology.
Diego M. Conti, Eduardo J. Correa, Alfonso Del Cuvillo, José D. Abdullatif, Francisco J. Alvarez‐Gutiérrez, Remedios Cárdenas Contreras, Stefan Cimbollek, Rocío Corrales Millán, Ana Gómez‐Bastero Fernández, Daniel Pérez‐Chada, Francisco Pérez‐Grimaldi, Alberto E. Rabino, Maria A. Romero‐Falcón, Marcela Soria, José Gregorio Soto‐Campos, Rosario B. Spuches, Juan Maza‐Solano   +16 more
wiley   +1 more source

Novel drug-delivery systems for patients with chronic rhinosinusitis [PDF]

, 2012
Silviu AlbuDepartment of Otolaryngology, University of Medicine and Pharmacy Cluj-Napoca, Cluj-Napoca, RomaniaAbstract: Chronic rhinosinusitis, one of the most common chronic medical complaints in the United States, seems to be increasing in incidence ...
Albu S
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