Results 91 to 100 of about 1,674,898 (231)

Morphological Sinus Features and Chronic Rhinosinusitis Risk: A Radiomics Study

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives Anatomical factors of the sinuses significantly impact the progression of chronic rhinosinusitis (CRS). This study aims to investigate the correlation between morphological sinus features and the risk of CRS onset to provide evidence‐based support for clinical management.
Song Luo, Xiang‐Hai Hu, Min Yin, Song Li, Lei Cheng   +4 more
wiley   +1 more source

Inflammatory Shift in Chronic Rhinosinusitis Amidst Guangzhou's Urbanization (2000–2018)

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) exhibits temporal and geographic diversity in pathological endotypes with progressive eosinophilic infiltration, while the underlying causes remain unclear. Current pathological endotypes determination relies on mean cell count per high‐power field, requiring accuracy optimization.
Ning Kang, Man‐Hou Chao, Xin Luo, Feng‐Wen Shan, Zi‐Xuan Hua, Ze‐Zhi Guo, Hua‐Mei Yan, He Zhang, Tong Wu, Min Zhou, Rui Zheng, Shuo Wu, Xue‐Kun Huang, Zhao‐Hui Shi, Ya‐Na Zhang, Ji Yang, Qin‐Tai Yang   +16 more
wiley   +1 more source

Eosinophilic asthma with chronic rhinosinusitis/nasal polyps and biologic agents

, 2019
The current understanding in severe asthma management is the targeted therapy approach with the evaluation of phenotypes and biomarkers. Therefore, personalized treatments are recently more prominent. Eosinophilic asthma with chronic rhinosinusitis/nasal
YILMAZ, İNSU
core   +1 more source

Research progress in the establishment of mouse models of chronic rhinosinusitis [PDF]

Xin yixue
Chronic nasal inflammation， such as rhinitis and sinusitis， is a common chronic disease that affects people’s quality of life for a long period of time. Its pathogenesis and mechanism are still unclear.
CHEN Yuan, SHEN Yang, WANG Ji, LU Tao, ZHENG Bowen, YANG Yucheng
doaj   +1 more source

Safety, Efficacy, and Mechanism of Action of Budesonide in Rhinitis and Rhinosinusitis: A Systematic Review

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Budesonide is a corticosteroid with unique pharmacokinetic and pharmacodynamic properties that has been a frontline treatment for patients with allergic rhinitis (AR) and chronic rhinosinusitis (CRS) since the 1990s. As research on budesonide continues to produce new insights, our aim was to synthesize recent investigations and ...
David W. Kennedy, Lei Cheng, De‐Yun Wang   +2 more
wiley   +1 more source

Eosinophilic myenteric ganglionitis is associated with functional intestinal obstruction [PDF]

, 2003
The diagnostic features and clinical course of three children (aged 1 month to 15 years) with severe functional intestinal obstruction and inflammation of the colonic lamina propria and myenteric plexus are described.
Smith, VV, Lindley, KJ, Milla, PJ, Schappi, MG   +3 more
core  

Periostin is an aggravating factor and predictive biomarker of eosinophilic chronic rhinosinusitis

, 2023
Background: Patients with eosinophilic chronic rhinosinusitis (ECRS) respond poorly to many treatment modalities. Overproduction of periostin in the nasal mucosa is reported to contribute to polyp formation.
Nobuo Ohta, Keigo Murakami, Kazuhiro Murakami, Teruyuki Sato, Hiroki Ikeda, Shion Shirane   +5 more
core   +1 more source

A case of recurrent chronic eosinophilic pneumonia after switching from benralizumab to dupilumab

Respiratory Medicine Case Reports
Dupilumab inhibits interleukin-4Rα and suppresses type 2 inflammation. Careful administration of dupilumab is required because it increases the blood eosinophil count secondary to a decrease in local eosinophil counts, sometimes resulting in eosinophilic
Daiki Nakashima, Eri Mori, Nobuyoshi Otori   +2 more
doaj   +1 more source

Immune Clues to Sinus Blues: Linking Biomarkers to Radiologic Score of Rhinosinusitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) is a prolonged inflammatory condition of the nasal and paranasal sinuses that significantly affects quality of life. This study examines the relationship between CRS severity (based on Lund‐Mackay [LM] scores), osteitis, and systemic inflammatory markers, including neutrophil‐to‐lymphocyte ratio (NLR ...
Lubna Khreesha, Amer Sawalha, Mohammad Darweesh, Qusai Elfadel, Mohammad Alzoubi, Saif Alhawadi, Faris Alsawair, Fares Habboub, Bashar Alsmady, Mohammad Aljarboa, Hashim Alhammouri   +10 more
wiley   +1 more source

Allergic bronchopulmonary aspergillosis complicated by eosinophilic chronic rhinosinusitis successfully treated with mepolizumab

Respirology Case Reports, 2019
A 67‐year‐old woman was admitted to our hospital because of frequent asthma attacks and refractory chronic rhinosinusitis. She was diagnosed with allergic bronchopulmonary aspergillosis (ABPA) concomitant with eosinophilic chronic rhinosinusitis (ECRS ...
Nobuhiro Matsumoto, Takafumi Shigekusa, Ayako Matsuo, Hironobu Tsubouchi, Shigehisa Yanagi, Masamitsu Nakazato   +5 more
doaj   +1 more source