Results 81 to 90 of about 1,778,131 (183)

Research Progress on Upper Airway Cough Syndrome

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Upper airway cough syndrome (UACS) has been identified as a significant contributor to chronic cough in various national guidelines. However, the complexity of its pathogenesis, the lack of clarity surrounding its diagnostic criteria, and its overlap with other etiologies of chronic cough present considerable challenges in both diagnosis and ...
Wan‐Ting Huang, Jia Chen
wiley   +1 more source

Metabolic and transcriptomic profiling between eosinophilic and non-eosinophilic chronic rhinosinusitis: Understanding subtype-specific metabolomic differences

Kühnel P, Damnig S, Reger B, et al. Metabolic and transcriptomic profiling between eosinophilic and non-eosinophilic chronic rhinosinusitis: Understanding subtype-specific metabolomic differences.
Damnig, Sharon, Reger, Bernd, Neumann, Judith Martha, Schürmann, Matthias, Sudhoff, Holger ; https://orcid.org/, Todt, Ingo, Scholtz, Lars-Uwe, Kühnel, Philipp ; https://orcid.org/, Niehaus, Karsten   +8 more
core   +1 more source

Allergic bronchopulmonary aspergillosis complicated by eosinophilic chronic rhinosinusitis successfully treated with mepolizumab

Respirology Case Reports, 2019
A 67‐year‐old woman was admitted to our hospital because of frequent asthma attacks and refractory chronic rhinosinusitis. She was diagnosed with allergic bronchopulmonary aspergillosis (ABPA) concomitant with eosinophilic chronic rhinosinusitis (ECRS ...
Nobuhiro Matsumoto, Takafumi Shigekusa, Ayako Matsuo, Hironobu Tsubouchi, Shigehisa Yanagi, Masamitsu Nakazato   +5 more
doaj   +1 more source

Maintenance of memory-type pathogenic Th2 cells in the pathophysiology of chronic airway inflammation

Inflammation and Regeneration, 2018
Background Immunological memory is critical for long-standing protection against microorganisms; however, certain antigen-specific memory CD4+ T helper (Th) cells drive immune-related pathology, including chronic allergic inflammation such as asthma. The
Kiyoshi Hirahara, Kenta Shinoda, Yusuke Endo, Tomomi Ichikawa, Toshinori Nakayama   +4 more
doaj   +1 more source

The Utility of Intranasal Corticosteroids in Association With Dupilumab for Chronic Rhinosinusitis With Nasal Polyposis: A Real‐Life Multicenter Study by a Tuscany Group

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Chronic rhinosinusitis with nasal polyps (CRSwNP) is a persistent inflammatory condition often associated with other type‐2 diseases. Dupilumab, a monoclonal antibody targeting IL‐4Rα, has revolutionized the treatment of severe CRSwNP.
Pietro Orlando, Giuseppe Licci, Marella Reale, Veronica Seccia, Alessia Giorli, Paolo Iannicelli, Dario Zaccari, Valentina Rossi, Jacopo Cambi, Stefano Berrettini, Marco Mandalà, Gianluca Leopardi, Antonio Sarno, Luca Muscatello, Simone Bocuzzi, Franco Trabalzini, Giandomenico Maggiore, Oreste Gallo   +17 more
wiley   +1 more source

sj-docx-2-ajr-10.1177_19458924221129903 - Supplemental material for The Percentage of PNAd-Expressing Vessels is Correlated with Disease Severity in Eosinophilic Chronic Rhinosinusitis

, 2022
Supplemental material, sj-docx-2-ajr-10.1177_19458924221129903 for The Percentage of PNAd-Expressing Vessels is Correlated with Disease Severity in Eosinophilic Chronic Rhinosinusitis by Eiichi Kato, Toshiki Tsutsumiuchi, Akifumi Muramoto, Takahiro ...
Shigeharu Fujieda (188194), Takahiro Tokunaga (444411), Eiichi Kato (1778782), Akifumi Muramoto (11212399), Motohiro Kobayashi (492004), Toshiki Tsutsumiuchi (11894546)   +5 more
core   +1 more source

Morphological Sinus Features and Chronic Rhinosinusitis Risk: A Radiomics Study

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives Anatomical factors of the sinuses significantly impact the progression of chronic rhinosinusitis (CRS). This study aims to investigate the correlation between morphological sinus features and the risk of CRS onset to provide evidence‐based support for clinical management.
Song Luo, Xiang‐Hai Hu, Min Yin, Song Li, Lei Cheng   +4 more
wiley   +1 more source

Inflammatory Shift in Chronic Rhinosinusitis Amidst Guangzhou's Urbanization (2000–2018)

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) exhibits temporal and geographic diversity in pathological endotypes with progressive eosinophilic infiltration, while the underlying causes remain unclear. Current pathological endotypes determination relies on mean cell count per high‐power field, requiring accuracy optimization.
Ning Kang, Man‐Hou Chao, Xin Luo, Feng‐Wen Shan, Zi‐Xuan Hua, Ze‐Zhi Guo, Hua‐Mei Yan, He Zhang, Tong Wu, Min Zhou, Rui Zheng, Shuo Wu, Xue‐Kun Huang, Zhao‐Hui Shi, Ya‐Na Zhang, Ji Yang, Qin‐Tai Yang   +16 more
wiley   +1 more source

Safety, Efficacy, and Mechanism of Action of Budesonide in Rhinitis and Rhinosinusitis: A Systematic Review

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Budesonide is a corticosteroid with unique pharmacokinetic and pharmacodynamic properties that has been a frontline treatment for patients with allergic rhinitis (AR) and chronic rhinosinusitis (CRS) since the 1990s. As research on budesonide continues to produce new insights, our aim was to synthesize recent investigations and ...
David W. Kennedy, Lei Cheng, De‐Yun Wang   +2 more
wiley   +1 more source

Rhinosinusitis Predispose Asthmatic Patients to Severe Bronchial Asthma [PDF]

In this study, we evaluated the relationship between rhinosinusitis to the severity of asthma in asthmatic patients. This cross-sectional study was conducted on 90 patients with asthma referring to Imam Khomeini Hospital in Ardabil city.
غفرانی, محسن, اناری, حسن, اعظمی, احد, حبیب زاده, الهام, شرقی, افشان   +4 more
core   +1 more source